CAJ | 학술논문

目的：探讨磁共振波谱分析(MRS)和弥散成像(DWI)对早期前列腺癌的诊断价值。方法选取我院2012年1月至2013年12月经病理证实的前列癌腺癌和良性前列腺增生患者各30例，均行MRS和DWI，同时选择同期前列腺炎患者30例作为前列腺炎组，对ADC值、(Cho+Cre)/Cit值及与病理诊断符合率进行比较。结果在扩散敏感度系数b=600 s/mm2、b=800 s/mm2时，前列腺癌组ADC值明显低于良性前列腺增生组和前列腺炎组，差异具有统计学意义(P<0.05)。前列腺癌组(Cho+Cre)/Cit值明显高于良性前列腺增生组和前列腺炎组，差异具有统计学意义(P<0.05)。MRS检查阳性26例，与病理检查符合率为86.55%，DWI检查阳性25例，与病理检查符合率为83.33%，MRS和DWI联合检查阳性29例，与病理检查符合率为96.67%，检出率明显提高。结论因前列腺癌组织微观结构和代谢水平关系密切，因此有必要采用MRS和弥散成像联合检测，以提高早期诊断准确率。
목적：탐토자공진파보분석(MRS)화미산성상(DWI)대조기전렬선암적진단개치。방법선취아원2012년1월지2013년12월경병리증실적전렬암선암화량성전렬선증생환자각30례，균행MRS화DWI，동시선택동기전렬선염환자30례작위전렬선염조，대ADC치、(Cho+Cre)/Cit치급여병리진단부합솔진행비교。결과재확산민감도계수b=600 s/mm2、b=800 s/mm2시，전렬선암조ADC치명현저우량성전렬선증생조화전렬선염조，차이구유통계학의의(P<0.05)。전렬선암조(Cho+Cre)/Cit치명현고우량성전렬선증생조화전렬선염조，차이구유통계학의의(P<0.05)。MRS검사양성26례，여병리검사부합솔위86.55%，DWI검사양성25례，여병리검사부합솔위83.33%，MRS화DWI연합검사양성29례，여병리검사부합솔위96.67%，검출솔명현제고。결론인전렬선암조직미관결구화대사수평관계밀절，인차유필요채용MRS화미산성상연합검측，이제고조기진단준학솔。
Objective To explore the value of resonance spectroscopy (MRS) and diffusion imaging (DWI) in the diagnosis of early prostate cancer. Methods From January 2012 to December 2013, 30 patients with prostate cancer and 30 patients with benign hyperplasia of prostate gland carcinoma, which were pathologically proved, were chosen as study objects. Both MRS and DWI were used in those patients. At the same period, 30 patients with prostatitis were chosen as prostatitis group. The ADC values, (Cho+cre)/cit value and its coincidence rate with the pathological diagnosis were compared. Results When the sensitivity in the diffusion coefficient was b=600 s/mm2 or b=800 s/mm2, the ADC values in prostate cancer group was significantly lower than those in benign prostatic hyper-plasia and prostatitis group with significant differences (P<0.05). The (Cho+cre)/cit value in prostate cancer group was significantly higher than those in benign prostatic hyperplasia and prostatitis group with significant differences (P<0.05). 26 patients were positive detected by MRS, and the coincidence rate with pathologic examination was 86.55%. 25 pa-tients were positive detected by DWI, and the coincidence rate with pathological examination was 83.33%. 29 cases were positive detected by MRS and DWI joint inspection, and the coincidence rate with pathologic examination was 96.67%. The detection rate was significantly improved. Conclusion Due to the microstructure of prostate cancer tis-sues and its close relationship to metabolism, it is necessary to adopt MRS combined with DWI to improve the accura-cy of early diagnosis.