临床心身疾病杂志
臨床心身疾病雜誌
림상심신질병잡지
JOURNAL OF CLINICAL PSYCHOSOMATIC DISEASES
2014年
4期
111-112
,共2页
海洛因依赖戒断综合征%丁丙诺啡%美沙酮%替代治疗%氟哌丁醇%东莨菪碱
海洛因依賴戒斷綜閤徵%丁丙諾啡%美沙酮%替代治療%氟哌丁醇%東莨菪堿
해락인의뢰계단종합정%정병낙배%미사동%체대치료%불고정순%동랑탕감
HDWS%buprenorphine%methadone%replacement therapy%haloperidol%scopolamine
目的：探讨丁丙诺啡治疗海洛因依赖戒断综合征的临床疗效。方法将521例海洛因依赖戒断综合征患者随机分为两组，研究组舌下含服丁丙诺啡，静脉滴注氟哌啶醇＋东莨菪碱治疗，对照组口服美沙酮治疗，观察2周。对两组临床疗效进行对比分析。结果研究组有效率为95．1％，对照组为75．1％，研究组有效率显著高于对照组（χ2＝41．99，P＜0．01）。结论舌下含服丁丙诺啡、静脉滴注氟哌啶醇＋东莨菪碱治疗海洛因依赖戒断综合征疗效显著，优于美沙酮替代治疗。
目的：探討丁丙諾啡治療海洛因依賴戒斷綜閤徵的臨床療效。方法將521例海洛因依賴戒斷綜閤徵患者隨機分為兩組，研究組舌下含服丁丙諾啡，靜脈滴註氟哌啶醇＋東莨菪堿治療，對照組口服美沙酮治療，觀察2週。對兩組臨床療效進行對比分析。結果研究組有效率為95．1％，對照組為75．1％，研究組有效率顯著高于對照組（χ2＝41．99，P＜0．01）。結論舌下含服丁丙諾啡、靜脈滴註氟哌啶醇＋東莨菪堿治療海洛因依賴戒斷綜閤徵療效顯著，優于美沙酮替代治療。
목적：탐토정병낙배치료해락인의뢰계단종합정적림상료효。방법장521례해락인의뢰계단종합정환자수궤분위량조，연구조설하함복정병낙배，정맥적주불고정순＋동랑탕감치료，대조조구복미사동치료，관찰2주。대량조림상료효진행대비분석。결과연구조유효솔위95．1％，대조조위75．1％，연구조유효솔현저고우대조조（χ2＝41．99，P＜0．01）。결론설하함복정병낙배、정맥적주불고정순＋동랑탕감치료해락인의뢰계단종합정료효현저，우우미사동체대치료。
Objective To explore the efficacy of buprenorphine in heroin depend-ence withdrawal syndrome (HDWS) .Methods A total of 521 HDWS patients were randomly assigned to two groups ,research group was treated with sublingually buccal buprenorphine and intravenous drip of haloperidol+scopolamine ,and control group took orally methadone for 2 weeks .Efficacies of two groups were contrastively analyzed .Results Effective rate was respectively 95 .1% in research and 75 .1% in con-trol group ,the former significantly higher than the latter (χ2 =41 .99 ,P<0 .01) .Conclusion Sublingually buccal buprenorphine and intravenous drip of haloperidol + scopolamine have an evident effect compared with methadone replacement therapy in HAWS .
