CAJ | 학술논문

观察清醒状态血氧饱和度大于90%的COPD患者夜间睡眠呼吸紊乱对动脉血氧的影响，为临床重视和治疗COPD夜间低氧血症、防止并发症提供依据。选择COPD患者66例，包括AECOPD 20例、COPD稳定期22例、重叠综合征组24例，设正常对照组10例。提示COPD患者夜间睡眠时存在低通气状态，以合并阻塞型睡眠呼吸暂停综合症最为严重，可使清醒状态下血氧饱和度大于90%的COPD患者夜间睡眠发生低氧血症，COPD病情严重程度与动脉血氧下降存在一定联系。
관찰청성상태혈양포화도대우90%적COPD환자야간수면호흡문란대동맥혈양적영향，위림상중시화치료COPD야간저양혈증、방지병발증제공의거。선택COPD환자66례，포괄AECOPD 20례、COPD은정기22례、중첩종합정조24례，설정상대조조10례。제시COPD환자야간수면시존재저통기상태，이합병조새형수면호흡잠정종합증최위엄중，가사청성상태하혈양포화도대우90%적COPD환자야간수면발생저양혈증，COPD병정엄중정도여동맥혈양하강존재일정련계。
Objective To investigate the effects of nocturnal sleep breathing disturbance on arterial oxygen saturation in chronic obstructive pulmonary disease (COPD) patients with wakingoxygen saturation of >90%. Sixty-six patients were divided into stable COPD group (n=22), acute embittering chronic obstructive pulmonary disease (AECOPD) group (n=20), overlap syndrome group (n=24) and control group (n=10). COPD patients with waking SaO2>90%are apt to show nocturnal hypoxemia. The disease situation is associated with the hyoxemia in patients with COPD.