CAJ | 학술논문

目的探讨帕金森病(Parkinson's disease,PD)患者生物运动感知能力.方法采用时距辨别任务,对45例原发性PD患者和45例正常对照组进行生物运动感知能力测试.结果正常对照组的主观相等点(point of subjective equality,PSE)为负值(-0.27±0.17),与检验值“0”相比差异有统计学意义(t=10.96,P＜0.01).PD患者组的PSE(-0.14±0.30)较正常对照组的PSE值明显减小,差异有统计学意义(t=2.63,P=0.01).PD早期组(H-Y 1-2级)的PSE值(-0.24±0.14)与正常对照组的PSE值之间差异无统计学意义(t=0.84,P=0.405),而PD晚期组(H-Y 3-4级)的PSE(0.02±0.39)负值基本消失,与正常对照组的PSE值之间差异有统计学意义(t=4.07,P=0.008).结论 PD患者存在生物运动感知障碍,且与病情的严重程度相关.
목적 탐토파금삼병(Parkinson's disease,PD)환자생물운동감지능력.방법 채용시거변별임무,대45례원발성PD환자화45례정상대조조진행생물운동감지능력측시.결과 정상대조조적주관상등점(point of subjective equality,PSE)위부치(-0.27±0.17),여검험치“0”상비차이유통계학의의(t=10.96,P＜0.01).PD환자조적PSE(-0.14±0.30)교정상대조조적PSE치명현감소,차이유통계학의의(t=2.63,P=0.01).PD조기조(H-Y 1-2급)적PSE치(-0.24±0.14)여정상대조조적PSE치지간차이무통계학의의(t=0.84,P=0.405),이PD만기조(H-Y 3-4급)적PSE(0.02±0.39)부치기본소실,여정상대조조적PSE치지간차이유통계학의의(t=4.07,P=0.008).결론 PD환자존재생물운동감지장애,차여병정적엄중정도상관.
Objective To explore the biological motion perception in Parkinson's disease (PD).Methods 45 individuals with idiopathic PD were compared with 45 matched healthy controls (HCs) using a duration discrimination task.Results The point of subjective equality(PSE) was negative value (-0.27±0.17) for health controls (HCs),and there was significant difference compared with "PSE =0" by one sample t test (t=10.96,P＜ 0.01).Compared with HCs,the PSE for PD patients (-0.14±0.30) significantly decreased (t=2.63,P=0.01).When further dividing PD into early stages (stage 1-2) and late stages (stage 3-4),significant difference was found between late-stage PD patients(0.02±0.39)and HCs (t=4.07,P=0.008),but not between early-stage PD patients (-0.24±0.14) and HCs (t=0.84,P=0.405).Conclusion There is biological motion perception disorder in PD patients and it is related to the severity of PD.