浙江体育科学
浙江體育科學
절강체육과학
ZHEJIANG SPORTS SCIENCE
2012年
5期
109-112
,共4页
有氧运动%脂肪组织%脂滴包被蛋白A
有氧運動%脂肪組織%脂滴包被蛋白A
유양운동%지방조직%지적포피단백A
aerobic exercise%adipose tissue%perilipin A
目的：研究8周有氧运动对肥胖大鼠腹内脂肪组织perilipin A基因表达的影响。方法：健康雄性SD大鼠60只（60～95g）,随机抽取10只作为普通膳食对照组（C）,喂养标准普通饲料。其余50只喂养高脂膳食,7周后建立肥胖大鼠模型16只,再随机分为2组：肥胖非运动组（Ob,n=8）和肥胖运动组（Ob-E,n=8）。8周后测定大鼠体重、血脂、腹内脂肪组织perilipin A mRNA表达。结果：肥胖不运动组（Ob组）大鼠体重、腹内脂肪总量、脂体比、血清TG、腹内脂肪组织perilipin A mRNA表达显著高于对照C组;肥胖运动组（Ob-E组）大鼠腹内脂肪总量、脂体比、血清TG、腹内脂肪组织perilipin A mRNA表达相比Ob组显著降低。结论：8周有氧跑台运动明显降低了高脂饮食肥胖大鼠的腹部脂肪含量,改善了血脂水平及明显降低腹内脂肪组织perilipin A mRNA表达。
目的：研究8週有氧運動對肥胖大鼠腹內脂肪組織perilipin A基因錶達的影響。方法：健康雄性SD大鼠60隻（60～95g）,隨機抽取10隻作為普通膳食對照組（C）,餵養標準普通飼料。其餘50隻餵養高脂膳食,7週後建立肥胖大鼠模型16隻,再隨機分為2組：肥胖非運動組（Ob,n=8）和肥胖運動組（Ob-E,n=8）。8週後測定大鼠體重、血脂、腹內脂肪組織perilipin A mRNA錶達。結果：肥胖不運動組（Ob組）大鼠體重、腹內脂肪總量、脂體比、血清TG、腹內脂肪組織perilipin A mRNA錶達顯著高于對照C組;肥胖運動組（Ob-E組）大鼠腹內脂肪總量、脂體比、血清TG、腹內脂肪組織perilipin A mRNA錶達相比Ob組顯著降低。結論：8週有氧跑檯運動明顯降低瞭高脂飲食肥胖大鼠的腹部脂肪含量,改善瞭血脂水平及明顯降低腹內脂肪組織perilipin A mRNA錶達。
목적：연구8주유양운동대비반대서복내지방조직perilipin A기인표체적영향。방법：건강웅성SD대서60지（60～95g）,수궤추취10지작위보통선식대조조（C）,위양표준보통사료。기여50지위양고지선식,7주후건립비반대서모형16지,재수궤분위2조：비반비운동조（Ob,n=8）화비반운동조（Ob-E,n=8）。8주후측정대서체중、혈지、복내지방조직perilipin A mRNA표체。결과：비반불운동조（Ob조）대서체중、복내지방총량、지체비、혈청TG、복내지방조직perilipin A mRNA표체현저고우대조C조;비반운동조（Ob-E조）대서복내지방총량、지체비、혈청TG、복내지방조직perilipin A mRNA표체상비Ob조현저강저。결론：8주유양포태운동명현강저료고지음식비반대서적복부지방함량,개선료혈지수평급명현강저복내지방조직perilipin A mRNA표체。
Objective:To study the effect of 8 weeks aerobic exercise on obese rats’adipose tissue perilipin gene A expression.Method:60 healthy male Sprague-Dawley rats(60~95g) were randomly selected 10 rats as normal dietary control group of rats(C,n=10),and fed with normal standard diet.The remaining 50 rats were feed high-fat diet.Seven weeks later,16 diet-induced-obesity rats models were established.They were randomly divided into two group: no-exercise group(Ob,n=8) and exercise group(Ob-E,n=8).8 weeks later,the body weight and serum lipid of rats,the perilipin A mRNA expression in visceral adipose tissue of rats were measured.Result: Compared with control group,the body weight,the total abdominal fat,total abdominal fat/body weight ratio,serum TG and the adipose tissue perilipin gene A expression of Ob group were evidently elevated;after 8 weeks aerobic exercise,compared with Ob group,the total abdominal fat,total abdominal fat/body weight ratio,serum TG and the adipose tissue perilipin gene A expression of Ob-E group were evidently fell.Conclusion: 8 weeks aerobic exercise evidently reduce the total abdominal fat,improved serum lipid levels and evidently reduce the adipose tissue perilipin gene A expression of obese rats fed by high-fat diet.
