CAJ | 학술논문

随着心血管疾病治疗技术的发展，各种金属血管支架作为治疗心血管疾病的最有效器械之一，已经越来越受到人们的关注。重点介绍了目前研究最广泛的2类可降解金属血管支架材料：镁基合金和铁基合金。总结了这2类血管支架用可降解金属材料的研究进展，血管支架器械的动物试验和临床试验研究成果。归纳了可降解金属血管支架的有限元结构设计、应力分析、体内体外降解性能和生物相容性等需要重点考虑的属性。指出了可降解金属血管支架目前存在的不足，并对可降解金属血管支架未来的研究方向和发展前景进行了展望。
수착심혈관질병치료기술적발전，각충금속혈관지가작위치료심혈관질병적최유효기계지일，이경월래월수도인문적관주。중점개소료목전연구최엄범적2류가강해금속혈관지가재료：미기합금화철기합금。총결료저2류혈관지가용가강해금속재료적연구진전，혈관지가기계적동물시험화림상시험연구성과。귀납료가강해금속혈관지가적유한원결구설계、응력분석、체내체외강해성능화생물상용성등수요중점고필적속성。지출료가강해금속혈관지가목전존재적불족，병대가강해금속혈관지가미래적연구방향화발전전경진행료전망。
With the development of new technology to treat cardiovascular disease (CVD) , cardiovascular stents have drawn more and more attention as one of the most effective device in the treatment of CVD. In this paper, we mainly fo- cused on two types of biodegradable metallic vascular stents which are mostly investigated nowadays, namely magnesium alloy stents and iron-based alloy stents. We summarized the research progresses on these biodegradable metallic alloys from the viewpoint of materials science in the present days and the animal experiments, clinic trail results of their stents as well. We overviewed about the finite element design, stress analysis, mechanical property, degradation performance, bio- compatibility of the biodegradable metallic stents. Finally, we pointed out the deficiency of current biodegradable metallic stent and their future research direction.