国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2013年
8期
701-703
,共3页
自拟补肾疏肝汤%溴隐亭%特发性高催乳素血症%不孕
自擬補腎疏肝湯%溴隱亭%特髮性高催乳素血癥%不孕
자의보신소간탕%추은정%특발성고최유소혈증%불잉
Chinese medicine%Bromocriptine%Hyperprolactinemia%Infertility
目的 探讨自拟补肾疏肝汤联合溴隐亭治疗特发性高催乳素血症不孕症的有效性.方法 将诊断为特发性高催乳血症不孕患者80例,随机分为两组各40例.对照组单用溴隐亭,治疗组在对照治疗的基础上加用自拟补肾疏肝汤治疗.比较两组治疗后临床症状、卵泡发育情况,统计排卵率、妊娠率；随访停药后血清中催乳素水平及妊娠结局,评估复发情况.结果 治疗组临床症状改善明显,排卵率、妊娠率、复发率分别为72.5％ (29/40)、60.0％ (24/40)、10.0％ (4/40)；对照组的排卵率、妊娠率、复发率分别为27.5％ (11/40)、20.0％ (8/40)、35.0％ (14/40),两组比较差异均有统计学意义(x2分别为16.200、13.333、7.168,P均＜0.05).治疗组所有妊娠者均为足月产,无流产、早产及胎儿畸形,妊娠结局良好.结论 自拟补肾疏肝汤联合溴隐亭治疗特发性高催乳素血症不孕具有临床疗效好、副作用小、排卵率及妊娠率高、复发率低及妊娠结局好的特点.
目的 探討自擬補腎疏肝湯聯閤溴隱亭治療特髮性高催乳素血癥不孕癥的有效性.方法 將診斷為特髮性高催乳血癥不孕患者80例,隨機分為兩組各40例.對照組單用溴隱亭,治療組在對照治療的基礎上加用自擬補腎疏肝湯治療.比較兩組治療後臨床癥狀、卵泡髮育情況,統計排卵率、妊娠率；隨訪停藥後血清中催乳素水平及妊娠結跼,評估複髮情況.結果 治療組臨床癥狀改善明顯,排卵率、妊娠率、複髮率分彆為72.5％ (29/40)、60.0％ (24/40)、10.0％ (4/40)；對照組的排卵率、妊娠率、複髮率分彆為27.5％ (11/40)、20.0％ (8/40)、35.0％ (14/40),兩組比較差異均有統計學意義(x2分彆為16.200、13.333、7.168,P均＜0.05).治療組所有妊娠者均為足月產,無流產、早產及胎兒畸形,妊娠結跼良好.結論 自擬補腎疏肝湯聯閤溴隱亭治療特髮性高催乳素血癥不孕具有臨床療效好、副作用小、排卵率及妊娠率高、複髮率低及妊娠結跼好的特點.
목적 탐토자의보신소간탕연합추은정치료특발성고최유소혈증불잉증적유효성.방법 장진단위특발성고최유혈증불잉환자80례,수궤분위량조각40례.대조조단용추은정,치료조재대조치료적기출상가용자의보신소간탕치료.비교량조치료후림상증상、란포발육정황,통계배란솔、임신솔；수방정약후혈청중최유소수평급임신결국,평고복발정황.결과 치료조림상증상개선명현,배란솔、임신솔、복발솔분별위72.5％ (29/40)、60.0％ (24/40)、10.0％ (4/40)；대조조적배란솔、임신솔、복발솔분별위27.5％ (11/40)、20.0％ (8/40)、35.0％ (14/40),량조비교차이균유통계학의의(x2분별위16.200、13.333、7.168,P균＜0.05).치료조소유임신자균위족월산,무유산、조산급태인기형,임신결국량호.결론 자의보신소간탕연합추은정치료특발성고최유소혈증불잉구유림상료효호、부작용소、배란솔급임신솔고、복발솔저급임신결국호적특점.
Objective To evaluate the clinical efficacy of the treatment of idiopathic hyperprolactinemia infertility by Chinese medicine combined with bromocriptine.Methods 80 patients diagnosed of idiopathic hyperprolactinemia infertility were randomly recruited into a control group and a experimental group.The control group was treated with bromocriptine alone and the experimental group was treated additionally with self-designed Bushen Shugan decoction on the basis of the control group.The improvement of the clinical symptoms and follicular development were compared between the two groups.The data of ovulation and pregnancy rate was collected.The serum prolactin level and pregnancy outcomes afterdrug withdrawal was followed up and the recurrences was evaluated.Results The follicular development of the experimental group was improved greatly.Its ovulation rate was 72.5％(29/40),pregnancy rate was 60.0％ (24/40) and recurrence rate was 10.0％ (4/40).The follicular development of the control group was not obvious.Its ovulation rate was 27.5％(11/40),pregnancy rate was 20.0％(8/40)and recurrence rate was 35.0％ (14/40).The difference between the two groups was statistically significant (x2＝ 16.200,13.333,7.168,P＜0.05).Besides,there was no miscarriage,premature delivery and fetal malformations in the experimental group.Conclusion The treatment of idiopathic hyperprolactinemia infertility by Chinese medicine combined with bromocriptine had the characteristics of sound clinical efficacy,little side effect,high ovulation and pregnancy rate,low recurrence and good pregnancy outcomes.
