CAJ | 학술논문

目的研究中晚期宫颈癌患者进行同步放化疗治疗的临床效果。方法我院选择2008年10月~2010年10月诊治的370例在IIb~IVa期宫颈癌患者，将其随机分为两组，观察组的180例患者在放疗的基础上运用20mg/m2的顺铂进行同步化疗，对照组的190例患者运用单纯放疗法进行治疗。结果通过对所选患者的结果进行比较，两组患者的近期疗效差异显著，有统计学意义（<0.05）；两组患者的无进展生存期（PFS)差异显著，有统计学意义（<0.05）；比较两组患者的2年生存率（OS），差异显著，有统计学意义（<0.05）。结论对于中晚期宫颈癌患者运用顺铂同步放化疗进行治疗，临床效果较为显著，便于治疗，值得在临床上大力推广使用。
목적연구중만기궁경암환자진행동보방화료치료적림상효과。방법아원선택2008년10월~2010년10월진치적370례재IIb~IVa기궁경암환자，장기수궤분위량조，관찰조적180례환자재방료적기출상운용20mg/m2적순박진행동보화료，대조조적190례환자운용단순방요법진행치료。결과통과대소선환자적결과진행비교，량조환자적근기료효차이현저，유통계학의의（<0.05）；량조환자적무진전생존기（PFS)차이현저，유통계학의의（<0.05）；비교량조환자적2년생존솔（OS），차이현저，유통계학의의（<0.05）。결론대우중만기궁경암환자운용순박동보방화료진행치료，림상효과교위현저，편우치료，치득재림상상대력추엄사용。
Objective To explore the clinical ef ects of concurrent radiotherapy and chemotherapy in the treatment of patients with advanced cervical cancer research.Methods 370 cases of patients with cervical carcinoma in stage IIb-Iva in our hospital in 2008 October~2010 year in October were randomly divided into two groups, 190 patients in the control group with simple radiotherapy treatment, 180 patients in the observation group in radiotherapy based on the use of 20mg per square metre of cis platinum synchronization chemotherapy.Results By comparing the results of selected patients,curative ef ects between two groups were significant,with statistical significance ( <0.05);The Progress Free Survival of two groups were significantly dif erent,with statistical significance ( <0.05);Compared two groups of patients with 2 year survival rate,significant dif erence was statistical y significant ( <0.05). Conclusion For patients with cisplatin in advanced cervical cancer 5-fluorouracil concurrent chemotherapy treatment,the clinical ef ect is significant,it is worth to popularize in clinical .