CAJ | 학술논문

目的：评价入院后48小时内平均血糖水平对非糖尿病急性心肌梗死(AMI)患者近期预后的影响。方法：收治非糖尿病AMI患者283例，根据入院48小时的2次的平均空腹血糖水平，将患者分为＜6.18mmol/L(1组)、6.1～7.88mmol/L(2组)、＞7.8mmol/L(3组)3组。组间比较不同平均空腹血糖水平的AMI患者临床特征、住院期间主要心脏事件及死亡的发生情况、住院治疗经过情况。结果：与1组比较，2组、3组中女性发生广泛前壁AMI的比例明显增多。随着平均空腹血糖的升高左室射血分数下降，恶性心律失常、心力衰竭的发生率和住院病死率升高，差异有统计学意义(P＜0.05)。对影响住院期间死亡率的多因素分析结果显示，高血压病、吸烟、平均空腹血糖、CK-MB峰值、左室射血分数对住院期间死亡率均有明显的影响。结论：入院48小时内平均空腹血糖升高是非糖尿病AMI住院患者死亡的独立危险因素。
목적：평개입원후48소시내평균혈당수평대비당뇨병급성심기경사(AMI)환자근기예후적영향。방법：수치비당뇨병AMI환자283례，근거입원48소시적2차적평균공복혈당수평，장환자분위＜6.18mmol/L(1조)、6.1～7.88mmol/L(2조)、＞7.8mmol/L(3조)3조。조간비교불동평균공복혈당수평적AMI환자림상특정、주원기간주요심장사건급사망적발생정황、주원치료경과정황。결과：여1조비교，2조、3조중녀성발생엄범전벽AMI적비례명현증다。수착평균공복혈당적승고좌실사혈분수하강，악성심률실상、심력쇠갈적발생솔화주원병사솔승고，차이유통계학의의(P＜0.05)。대영향주원기간사망솔적다인소분석결과현시，고혈압병、흡연、평균공복혈당、CK-MB봉치、좌실사혈분수대주원기간사망솔균유명현적영향。결론：입원48소시내평균공복혈당승고시비당뇨병AMI주원환자사망적독립위험인소。
Objective To explore the Influence of average fasting blood glucose level within 48 hours after admission on the recent prognosis of patients with non-diabetic acute myocardial infarction(AMI).Methods:283 AMI patients with non-diabetic were selected.They were divided into three groups according to two times average fasting blood glucose levels within 48 hours after admission.The three groups were <6.1mmol/L group,6.1~7.8mmol/L group, >7.8mmol/L group.The clinical features,major cardiac events during hospitalization,the occurrence of death and the inpatient treatment situstion of AMI patients with different average fasting blood glucose levels were compared.Results:Compared with 1 group,the proportion of women and extensive anterior wall AMI of 2 group and 3 group were significantly increased. <br> With the average fasting blood glucose level was increased,the left ventricular ejection fraction was declined,the incidence rate of malignant arrhythmias and heart failure and the hospital mortality were increased.while have statistical significance(P<0.05).The multivariate analysis of hospital mortality indicated that hypertension,smoking,average fasting blood glucose,CK-MB peak,left ventricular ejection fraction had a significant effect on hospitalization mortality.Conclusion:The increasing average fasting blood glucose with 48 hours after admission is an independent risk factor for in-hospital death of AMI patients with non-diabetic.