CAJ | 학술논문

目的：探讨新生儿高胆红素血症对婴幼儿智力发育的远期影响。方法选择66例高胆红素血症患儿作为观察组，另选取同期60例健康新生儿纳入对照组，对2组新生儿的出生资料、临床诊疗资料及随访记录进行回顾性分析。结果观察组新生儿神经行为评分（NBNA）明显低于对照组（P<0.01）；随访期间在大运动、精细动作、适应能力、语言和社会交往方面比较，在12个月、24个月时的发育商评分均显著低于对照组（P<0.01）。结论高胆红素血症对新生儿神经行为能力和婴幼儿智能发育均有一定影响，因此在临床中应积极处理新生儿高胆红素血症，及早进行治疗干预，防治高胆红素血症对婴幼儿智能发育的危害。
목적：탐토신생인고담홍소혈증대영유인지력발육적원기영향。방법선택66례고담홍소혈증환인작위관찰조，령선취동기60례건강신생인납입대조조，대2조신생인적출생자료、림상진료자료급수방기록진행회고성분석。결과관찰조신생인신경행위평분（NBNA）명현저우대조조（P<0.01）；수방기간재대운동、정세동작、괄응능력、어언화사회교왕방면비교，재12개월、24개월시적발육상평분균현저저우대조조（P<0.01）。결론고담홍소혈증대신생인신경행위능력화영유인지능발육균유일정영향，인차재림상중응적겁처리신생인고담홍소혈증，급조진행치료간예，방치고담홍소혈증대영유인지능발육적위해。
Objective To observe the effect of Neonatal hyperbilirubinemia on mental development of infants. Methods 66 children with hyperbilirubinemia treated in our hospital from January 2009 to January 2011 were selected into the observation group. While during the period 60 healthy newborns in our hospital were selected into the control group. The birth data, clinical diagnosis and treatment information and follow-up note of the newborns in the 2 groups were analyzed retrospectively. Results Children of neonatal hyperbilirubinemia were worse in neural behavior than the normal babies. The control group was better evidently than the observation group during the follow-up period (P<0.05). For the intelligence score comparison of gross motor, fine motor, adaptation ability, language ability and social ability , the observation group were lower obviously than the control group in 12 and 24 months (P<0.05). Conclusion Children of neonatal hyperbilirubinemia were worse in neural behavior and intelligence during the follow -up period after recovery. So we should strengthen on the monitor of neonatal serum bilirubin in the clinical, and make therapeutic intervention early to reduce the incidence of hyperbilirubinemia.