CAJ | 학술논문

目的：研究虫类散剂对炎性颈神经根动物模型的抗炎效果，应用于临床治疗。方法建立炎性颈神经根的大鼠模型，配置不同浓度的虫类散剂（三七三虫散）分对照组、治疗组（中剂量治疗组和高剂量治疗组）进行干预，观察3d、1w、2w时大鼠神经根炎性肉芽肿的重量、炎性神经根IL-1、IL-6的含量，对各项结果进行统计分析。结果虫类散剂（三七三虫散）对于大鼠神经根炎性肉芽肿具有显著的抑制作用，对于大鼠颈神经根IL-1、IL-6含量明显抑制，在1周时表现显著。而且高剂量组较中剂量组各项指标优势更为明显。结论虫类散剂（三七三虫散）对于炎性神经根具有良好的抗炎作用，具有疗效好、服用方便等优点，是治疗神经根型颈椎病的临床有效方剂。
목적：연구충류산제대염성경신경근동물모형적항염효과，응용우림상치료。방법건립염성경신경근적대서모형，배치불동농도적충류산제（삼칠삼충산）분대조조、치료조（중제량치료조화고제량치료조）진행간예，관찰3d、1w、2w시대서신경근염성육아종적중량、염성신경근IL-1、IL-6적함량，대각항결과진행통계분석。결과충류산제（삼칠삼충산）대우대서신경근염성육아종구유현저적억제작용，대우대서경신경근IL-1、IL-6함량명현억제，재1주시표현현저。이차고제량조교중제량조각항지표우세경위명현。결론충류산제（삼칠삼충산）대우염성신경근구유량호적항염작용，구유료효호、복용방편등우점，시치료신경근형경추병적림상유효방제。
Objective Study insects cervical nerve root powder for animal models of inflammatory anti-inflammatory ef ects, used in clinical treatment. Methods:Establishment of inflammatory cervical nerve root in a rat model, configuration, dif erent concentrations of insects powder (Sanqisanchongsan) of the control group, the treatment group (middle dose group and high dose group) to intervene, observed three days, a week, 2 weeks inflammatory granuloma in rat nerve root weight, inflammatory nerve root IL-1, IL-6 levels, the various results were statistical y analyzed. Result:Insects powder (Sanqisanchongsan) nerve root granuloma in rats significantly inhibited in rats cervical nerve root IL-1, IL-6 was significantly inhibited, in a week when the performance is remarkable. And the high-dose group than in the middle dose group the indicators more obvious advantages. Conclusion:Insects powder (Sanqisanchongsan) for inflammatory nerve root has a good anti-inflammatory ef ects, with good ef icacy, easy to take, etc., is the treatment of nerve root type cervical spondylosis clinical y ef ective prescription.