中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
4期
779-782
,共4页
循环肿瘤细胞%细胞游离DNA
循環腫瘤細胞%細胞遊離DNA
순배종류세포%세포유리DNA
Circulating tumor cells%Cell-free DNA
循环肿瘤细胞(CTCs)和细胞游离DNA(cfDNA)近十年间得到了肿瘤学界的广泛关注。大量的文献报道CTCs和cfDNA在肿瘤诊断、疗效监测和预后评估方面具有价值。本综述将系统介绍CTCs和cfDNA的生物学特性以及临床意义,并探讨CTCs和cfDNA从基础研究到肿瘤临床转化的前景和挑战。
循環腫瘤細胞(CTCs)和細胞遊離DNA(cfDNA)近十年間得到瞭腫瘤學界的廣汎關註。大量的文獻報道CTCs和cfDNA在腫瘤診斷、療效鑑測和預後評估方麵具有價值。本綜述將繫統介紹CTCs和cfDNA的生物學特性以及臨床意義,併探討CTCs和cfDNA從基礎研究到腫瘤臨床轉化的前景和挑戰。
순배종류세포(CTCs)화세포유리DNA(cfDNA)근십년간득도료종류학계적엄범관주。대량적문헌보도CTCs화cfDNA재종류진단、료효감측화예후평고방면구유개치。본종술장계통개소CTCs화cfDNA적생물학특성이급림상의의,병탐토CTCs화cfDNA종기출연구도종류림상전화적전경화도전。
Circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have gained increasing interests during the decade. A wealth of information indicating the potential value of CTCs and cfDNA for cancer diagnosis, monitoring of the efficacy of anticancer therapies and prognosis has emerged. In this review, we communicate the knowledge obtained through analysis the biology and potential clinical use of CTCs and cfDNA to oncologies, moreover, discuss their impact and challenges on the management of patients with cancer.