中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
16期
2607-2612
,共6页
姚辉%卢华定%徐义春%赵慧清%吕璐璐
姚輝%盧華定%徐義春%趙慧清%呂璐璐
요휘%로화정%서의춘%조혜청%려로로
生物材料%材料相容性%高分子泡沫材料%负压引流%足踝部软组织%缺损%游离植皮%创面修复
生物材料%材料相容性%高分子泡沫材料%負壓引流%足踝部軟組織%缺損%遊離植皮%創麵脩複
생물재료%재료상용성%고분자포말재료%부압인류%족과부연조직%결손%유리식피%창면수복
biocompatible materials%drainage%soft tissue injuries%skin transplantation
背景:有研究表明,对于开放性骨折伴软组织缺损在不可能关闭软组织缺损和未找到可用的肌肉和肌皮瓣前,将负压封闭引流高分子泡沫材料作为人工替代皮肤覆盖创面是一种较好的方法。目的:观察高分子泡沫材料负压封闭引流修复足踝部皮肤软组织缺损的疗效。方法:选择25例足踝部皮肤软组织缺损患者,其中14例采用高分子泡沫材料负压封闭引流技术联合拉网植皮治疗,另11例采用传统换药联合植皮打包覆盖创面治疗。比较两组治疗的临床效果差异。结果与结论:负压封闭引流组中10例植皮完全成活,成活率为71%;另4例通过换药最终覆盖创面。传统换药组中6例植皮完全成活,成活率为55%;剩余5例中3例通过换药愈合,2例行二次植皮。两组植皮成活率差异无显著性意义(P >0.05)。负压封闭引流组等待二期手术时间、二期手术前换药次数及缺损完全修复时间均少于传统换药组(P <0.05)。提示高分子泡沫材料负压封闭引流技术可加快游离植皮修复足踝部皮肤软组织缺损创面愈合速度,缩短病程。
揹景:有研究錶明,對于開放性骨摺伴軟組織缺損在不可能關閉軟組織缺損和未找到可用的肌肉和肌皮瓣前,將負壓封閉引流高分子泡沫材料作為人工替代皮膚覆蓋創麵是一種較好的方法。目的:觀察高分子泡沫材料負壓封閉引流脩複足踝部皮膚軟組織缺損的療效。方法:選擇25例足踝部皮膚軟組織缺損患者,其中14例採用高分子泡沫材料負壓封閉引流技術聯閤拉網植皮治療,另11例採用傳統換藥聯閤植皮打包覆蓋創麵治療。比較兩組治療的臨床效果差異。結果與結論:負壓封閉引流組中10例植皮完全成活,成活率為71%;另4例通過換藥最終覆蓋創麵。傳統換藥組中6例植皮完全成活,成活率為55%;剩餘5例中3例通過換藥愈閤,2例行二次植皮。兩組植皮成活率差異無顯著性意義(P >0.05)。負壓封閉引流組等待二期手術時間、二期手術前換藥次數及缺損完全脩複時間均少于傳統換藥組(P <0.05)。提示高分子泡沫材料負壓封閉引流技術可加快遊離植皮脩複足踝部皮膚軟組織缺損創麵愈閤速度,縮短病程。
배경:유연구표명,대우개방성골절반연조직결손재불가능관폐연조직결손화미조도가용적기육화기피판전,장부압봉폐인류고분자포말재료작위인공체대피부복개창면시일충교호적방법。목적:관찰고분자포말재료부압봉폐인류수복족과부피부연조직결손적료효。방법:선택25례족과부피부연조직결손환자,기중14례채용고분자포말재료부압봉폐인류기술연합랍망식피치료,령11례채용전통환약연합식피타포복개창면치료。비교량조치료적림상효과차이。결과여결론:부압봉폐인류조중10례식피완전성활,성활솔위71%;령4례통과환약최종복개창면。전통환약조중6례식피완전성활,성활솔위55%;잉여5례중3례통과환약유합,2례행이차식피。량조식피성활솔차이무현저성의의(P >0.05)。부압봉폐인류조등대이기수술시간、이기수술전환약차수급결손완전수복시간균소우전통환약조(P <0.05)。제시고분자포말재료부압봉폐인류기술가가쾌유리식피수복족과부피부연조직결손창면유합속도,축단병정。
BACKGROUND:Preliminary studies have showed that vacuum sealing drainage based on wound surface dressing biomaterials is a good method to cover the wound as succedaneous peau when the soft tissuedefects along with open fracture cannot be completely repaired during the first operation. OBJECTIVE:To explore the efficacy of vacuum sealing drainage based on wound surface dressing biomaterials in repair of soft tissue defects of foot and ankle. METHODS:Fourteen patients with soft tissue defects of foot and ankle were treated using free skin graft combined with vacuum sealing drainage technique. Meanwhile, the traditional skin graft after wound dressing changes was applied in another 11 patients. The clinical outcomes were compared between two groups. RESULTS AND CONCLUSION:The transplanted skin in 10 cases of the vacuum sealing drainage group survived. The total survival rate was 71%, and surgical dressing change was applied in the left four patients to finaly cover the wound. By comparison, the transplanted skin in four cases of the traditional group survived. The total survival rate was 54%. To finish the wound, three of the left patients were turned to surgical dressing change and two of them stil needed skin graft operation once more. The total survival rate between the two groups has no statistical significance(P > 0.05). The therapeutic procedure noted that the time waiting for the secondary surgical visit, times for dressing change before the second intervention and the time for final union between the two groups were statisticaly different (P < 0.05). So the vacuum sealing drainage based on wound surface dressing biomaterials may accelerate the repair of soft tissue defects of foot and ankle when using the free skin graft operation.