中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
42期
6789-6794
,共6页
徐军%李开宾%曲庆%黄忠%张宏
徐軍%李開賓%麯慶%黃忠%張宏
서군%리개빈%곡경%황충%장굉
组织构建%组织工程%滚法%推拿%生物动力学%实验装置%国家自然科学基金
組織構建%組織工程%滾法%推拿%生物動力學%實驗裝置%國傢自然科學基金
조직구건%조직공정%곤법%추나%생물동역학%실험장치%국가자연과학기금
biomechanics%cells%calcium
背景:手法力学刺激能经过与各种细胞结合产生多类型丰富的转换结果从而启动机体多种生理调节功能。目的:分析推拿滚法能够提高细胞Ca2+通道的原因。方法:建立通过一套生物动力学实验装置,由压力发生装置、压强形成装置、压强显示装置以及相关的压强数据记录装置构成。通过压强显示、数据传输及数据记录、信号采集及处理、压强信号的采集、信号采集的控制及处理、信号无线传输及接收系统、显示系统、存储系统、系统实现功能及系统软件工作设计等环节完成推拿滚法应用生物力学对骨骼肌正常细胞和损伤细胞内Ca 2+浓度的影响。结果与结论:实验结果表明,滚法样刺激对于骨骼肌正常细胞和损伤细胞内Ca 2+浓度均有降低效果。提示由于滚法样刺激干预,使损伤细胞中细胞内的Ca2+超载得以改善,细胞内Ca2+浓度降低。在滚法样刺激与正弦力学刺激比较中,滚法样刺激的作用效果明显优于正弦力学刺激。
揹景:手法力學刺激能經過與各種細胞結閤產生多類型豐富的轉換結果從而啟動機體多種生理調節功能。目的:分析推拿滾法能夠提高細胞Ca2+通道的原因。方法:建立通過一套生物動力學實驗裝置,由壓力髮生裝置、壓彊形成裝置、壓彊顯示裝置以及相關的壓彊數據記錄裝置構成。通過壓彊顯示、數據傳輸及數據記錄、信號採集及處理、壓彊信號的採集、信號採集的控製及處理、信號無線傳輸及接收繫統、顯示繫統、存儲繫統、繫統實現功能及繫統軟件工作設計等環節完成推拿滾法應用生物力學對骨骼肌正常細胞和損傷細胞內Ca 2+濃度的影響。結果與結論:實驗結果錶明,滾法樣刺激對于骨骼肌正常細胞和損傷細胞內Ca 2+濃度均有降低效果。提示由于滾法樣刺激榦預,使損傷細胞中細胞內的Ca2+超載得以改善,細胞內Ca2+濃度降低。在滾法樣刺激與正絃力學刺激比較中,滾法樣刺激的作用效果明顯優于正絃力學刺激。
배경:수법역학자격능경과여각충세포결합산생다류형봉부적전환결과종이계동궤체다충생리조절공능。목적:분석추나곤법능구제고세포Ca2+통도적원인。방법:건립통과일투생물동역학실험장치,유압력발생장치、압강형성장치、압강현시장치이급상관적압강수거기록장치구성。통과압강현시、수거전수급수거기록、신호채집급처리、압강신호적채집、신호채집적공제급처리、신호무선전수급접수계통、현시계통、존저계통、계통실현공능급계통연건공작설계등배절완성추나곤법응용생물역학대골격기정상세포화손상세포내Ca 2+농도적영향。결과여결론:실험결과표명,곤법양자격대우골격기정상세포화손상세포내Ca 2+농도균유강저효과。제시유우곤법양자격간예,사손상세포중세포내적Ca2+초재득이개선,세포내Ca2+농도강저。재곤법양자격여정현역학자격비교중,곤법양자격적작용효과명현우우정현역학자격。
BACKGROUND:Methods after mechanical stimulation can be combined with various kinds of cells to produce many conversion types so as to start the various physiological functions of the body. OBJECTIVE:To analysis the reason why rol ing massage can improve the intracellular concentration of Ca2+METHODS:A biodynamic experimental device was set up, composed of pressure generating device, pressure forming device, pressure display device and related data recording device. We detected the effects of rol ing massage on Ca . 2+concentration in normal skeletal muscle cells and damaged cells through the different functions of the experimental device and system software. These functions consisted of pressure display, data transmission and recording, signal acquisition and processing, pressure signal acquisition, control and processing of signal acquisition, wireless signal transmission and receiving system, display system, storage system, system implementation function. RESULTS AND CONCLUSION:The experiment results showed that rol ing massage could reduce the Ca 2+concentration in the normal skeletal muscle cells and damaged cells. These findings suggest that rol ing massage can improve the overload of intracellular Ca2+in damaged cells, and it is superior to the sinusoidal mechanical stimulus.