CAJ | 학술논문

蚯蚓纤溶酶是从蚯蚓中分离的一种丝氨酸蛋白水解酶，有抗凝溶血栓、抗癌抗肿瘤、抗炎、神经修复等作用，在临床上是预防和治疗血栓疾病的有效药物。本文对蚯蚓纤溶酶的分离纯化与药理作用加以概述，为临床蚯蚓溶栓药物的研究提供依据。
구인섬용매시종구인중분리적일충사안산단백수해매，유항응용혈전、항암항종류、항염、신경수복등작용，재림상상시예방화치료혈전질병적유효약물。본문대구인섬용매적분리순화여약리작용가이개술，위림상구인용전약물적연구제공의거。
The earthworm fibrinolytic enzyme, as a serine protease from the earthworm, has the effect of thrombolytic, anticoagulant, anticancer, anti-inflammatory, nerve repair, and so on. It is an effective drug for clinical prevention and treatment of thromboembolic diseases. This article described the separa- tion, purification and clinical effect of earthworm fibrinolytic enzyme, and provided the basics for clinical studies.