CAJ | 학술논문

目的：观察格列吡嗪与二甲双胍合用治疗2型糖尿病患者，测量其空腹血糖，糖化血红蛋白，餐后2h血糖，肾功能，血脂，体重指数。方法把38例2型糖尿病患者随机分为两组，各19个病例。治疗组使用格列吡嗪和二甲双胍，对照组采用格列吡嗪，治疗3个月。观察两组治疗前后的空腹血糖，糖化血红蛋白，和餐后2h血糖，肾功能，血脂和体重指数的变化。结果两组治疗前后组，空腹血糖，餐后2h血糖，糖化血红蛋白下降。两组比较差异有统计学意义。结论格列吡嗪与二甲双胍合用可以更好的使空腹血糖，餐后2h血糖，糖化血红蛋白下降，并能引起血脂和体重指数下降。
목적：관찰격렬필진여이갑쌍고합용치료2형당뇨병환자，측량기공복혈당，당화혈홍단백，찬후2h혈당，신공능，혈지，체중지수。방법파38례2형당뇨병환자수궤분위량조，각19개병례。치료조사용격렬필진화이갑쌍고，대조조채용격렬필진，치료3개월。관찰량조치료전후적공복혈당，당화혈홍단백，화찬후2h혈당，신공능，혈지화체중지수적변화。결과량조치료전후조，공복혈당，찬후2h혈당，당화혈홍단백하강。량조비교차이유통계학의의。결론격렬필진여이갑쌍고합용가이경호적사공복혈당，찬후2h혈당，당화혈홍단백하강，병능인기혈지화체중지수하강。
Objective To observe glipizide in combination with metformin in patients with type 2 diabetes mel itus, fasting glucose, glycosylated hemoglobin, blood sugar 2 hours after meal, renal function, blood lipid, body mass index. Methods 38 patients with type 2 diabetes were randomly divided into two groups, each 19 cases. Treatment group using glipizide and metformin, control group adopts glipizide, treatment for 3 months. Observe two groups before and after treatment, the fasting glucose, glycosylated hemoglobin, and blood sugar 2 hours after meal, the change of renal function, blood lipid, and body mass index. Results In the two groups before and after treatment group, fasting blood glucose, blood sugar 2 hours after meal, glycosylated hemoglobin decreased. Conclusion Glipizide in combination with metformin can bet er control of fasting blood glucose, blood sugar 2 hours after meal, glycosylated hemoglobin, and can cause blood lipid and body mass index decline.