CAJ | 학술논문

阿维菌素制剂是广谱高效抗寄生虫药物，不但在畜牧养殖中长期使用，在渔业生产上对鱼类体内外寄生的线虫及节肢动物等也有较好的驱杀效果，已在水产养殖中广泛应用。但是，在水环境中，阿维菌素对鱼类生物毒性较大，如果使用不当，会对鱼类、水生动物及渔业生态系统造成影响。论文对阿维菌素的作用机理、药物毒性、药动学、鱼类养殖中的应用和残留检测方法等方面进行概述，重点分析了阿维菌素在鱼体内的检测方法、最高残留限量和药物动力学，旨在为评价阿维菌素对水生生物的毒害、控制药物残留等研究提供参考。
아유균소제제시엄보고효항기생충약물，불단재축목양식중장기사용，재어업생산상대어류체내외기생적선충급절지동물등야유교호적구살효과，이재수산양식중엄범응용。단시，재수배경중，아유균소대어류생물독성교대，여과사용불당，회대어류、수생동물급어업생태계통조성영향。논문대아유균소적작용궤리、약물독성、약동학、어류양식중적응용화잔류검측방법등방면진행개술，중점분석료아유균소재어체내적검측방법、최고잔류한량화약물동역학，지재위평개아유균소대수생생물적독해、공제약물잔류등연구제공삼고。
Avermectin is a broad-spectrum antiparasitic agent .Due to its therapeutic effects ,it has widely been used in aquaculture .It is not only used in livestock ,but it has also been extensively used in fishery production .in parasitic nematodes and arthropods .However ,if avermectin is improperly used in aquacul-ture ,it results toxic effects in an aqueous environment and aquatic ecosystems .The present review focused on avermectin's action mechanism ,drug toxicity and pharmacokinetics in aquatic animals .And this review also selectively analyzed the residue detection method and maximum residue limit in order to provide a ref-erence to the research of assessing avermectin's toxicity and the control of avermectin's residue effects on a-quatic organism .