国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
18期
2858-2861
,共4页
右美托咪定%机械通气%镇静评分%谵妄发生率
右美託咪定%機械通氣%鎮靜評分%譫妄髮生率
우미탁미정%궤계통기%진정평분%섬망발생솔
Dexmedetomidine%Mechanical ventilation%Ramsay%Delirium incidence rate
目的 探讨右美托咪定镇静效应及其对机械通气患者的睡眠情况及谵妄发生率的影响.方法 对2011年1月至2012年12月进入我院重症加强护理病房(intensive care unit,ICU)的60例术后需机械通气患者,分别应用右美托咪定及咪唑安定(各30例)联合舒芬太尼实施镇静镇痛,依据Ramsay评分标准,维持适当的镇静深度.比较两组患者术后留置气管插管时间、机械通气时间和入住ICU的天数,镇静镇痛药物的总量,用药后不同时间段的Ramsay分值、疼痛视觉模拟评分(visual analogue scale,VAS)、ICU谵妄诊断的意识模糊评估法(confusion assessment method for the diagnosis of delirium in the ICU,CAM-ICU).结果 A、B两组术后留置气管插管时间、机械通气的时间和入住ICU的天数存在统计学差异(P＜0.01),阿森斯失眠量表评分及谵妄发生率也有非常显著的统计学差异(P＜0.01).结论 右美托咪定能较好地改善机械通气患者的睡眠情况,降低谵妄发生率.
目的 探討右美託咪定鎮靜效應及其對機械通氣患者的睡眠情況及譫妄髮生率的影響.方法 對2011年1月至2012年12月進入我院重癥加彊護理病房(intensive care unit,ICU)的60例術後需機械通氣患者,分彆應用右美託咪定及咪唑安定(各30例)聯閤舒芬太尼實施鎮靜鎮痛,依據Ramsay評分標準,維持適噹的鎮靜深度.比較兩組患者術後留置氣管插管時間、機械通氣時間和入住ICU的天數,鎮靜鎮痛藥物的總量,用藥後不同時間段的Ramsay分值、疼痛視覺模擬評分(visual analogue scale,VAS)、ICU譫妄診斷的意識模糊評估法(confusion assessment method for the diagnosis of delirium in the ICU,CAM-ICU).結果 A、B兩組術後留置氣管插管時間、機械通氣的時間和入住ICU的天數存在統計學差異(P＜0.01),阿森斯失眠量錶評分及譫妄髮生率也有非常顯著的統計學差異(P＜0.01).結論 右美託咪定能較好地改善機械通氣患者的睡眠情況,降低譫妄髮生率.
목적 탐토우미탁미정진정효응급기대궤계통기환자적수면정황급섬망발생솔적영향.방법 대2011년1월지2012년12월진입아원중증가강호리병방(intensive care unit,ICU)적60례술후수궤계통기환자,분별응용우미탁미정급미서안정(각30례)연합서분태니실시진정진통,의거Ramsay평분표준,유지괄당적진정심도.비교량조환자술후류치기관삽관시간、궤계통기시간화입주ICU적천수,진정진통약물적총량,용약후불동시간단적Ramsay분치、동통시각모의평분(visual analogue scale,VAS)、ICU섬망진단적의식모호평고법(confusion assessment method for the diagnosis of delirium in the ICU,CAM-ICU).결과 A、B량조술후류치기관삽관시간、궤계통기적시간화입주ICU적천수존재통계학차이(P＜0.01),아삼사실면량표평분급섬망발생솔야유비상현저적통계학차이(P＜0.01).결론 우미탁미정능교호지개선궤계통기환자적수면정황,강저섬망발생솔.
Objective To study the effects of dexmedetomidine to sleep and delirium incidence rate of the patients with mechanical ventilation~ Methods From Jan 2011 to Dec 2012,60 patients with mechanical ventilation in intensive care unit (ICU) of our hospital were applicated with dexmedetomidine or imidazole with dexmedetomidine (30 cases in each group) respectively,ramsay score was the criterion to maintain appropriate calm depth.In the two groups,we compared intubation remaining time,mechanical ventilation time in postoperative of endotracheal indwelling and days in ICU,and implementation calm and analgesic drug,and ramsay,the score of visual analogue scale (VAS),the confusion assessment method for the intensive care unit (CAM-ICU),grading Criterion.Results Intubation remaining time,mechanical ventilation time and days in ICU of dexmedetomidine group were better than those of imidazole group (P＜0.05),and the incidence of insomnia,delirium were much better than those in imidazole group (P＜0.01).Conclusion Dexmedetomidine can significantly reduce the incidence of insomnia and delirium of patients with mechanical ventilation.
