CAJ | 학술논문

目的观察口炎清颗粒联合阿昔洛韦治疗婴幼儿疱疹性龈口炎的临床疗效.方法随机将2012年2月至2012年5月于广州市妇女儿童医疗中心口腔科就诊的患有疱疹性龈口炎的90例患儿分成口炎清颗粒联合阿昔洛韦治疗组和阿昔洛韦对照组,各45例.观察两组临床疗效(口腔溃疡持续天数、发热情况、进食困难程度)及不良反应.结果总共有78例患儿参与并完成本研究,其中40例是治疗组,38例是对照组.治疗组患儿口腔溃疡持续的时间明显短于对照组,其发热及进食水困难症状消失明显早于对照组.统计学数据结果表明,治疗组与对照组临床疗效差异有统计学意义(P＜0.05),但治疗组流涎症状与对照组相比,差异无统计学意义(P＜0.05).结论口炎清颗粒与阿昔洛韦联合用药能有效缓解疱疹性龈口炎引起的疼痛,减少溃疡持续天数,是治疗疱疹性龈口炎的一种有效的治疗方法.
목적 관찰구염청과립연합아석락위치료영유인포진성간구염적림상료효.방법 수궤장2012년2월지2012년5월우엄주시부녀인동의료중심구강과취진적환유포진성간구염적90례환인분성구염청과립연합아석락위치료조화아석락위대조조,각45례.관찰량조림상료효(구강궤양지속천수、발열정황、진식곤난정도)급불량반응.결과 총공유78례환인삼여병완성본연구,기중40례시치료조,38례시대조조.치료조환인구강궤양지속적시간명현단우대조조,기발열급진식수곤난증상소실명현조우대조조.통계학수거결과표명,치료조여대조조림상료효차이유통계학의의(P＜0.05),단치료조류연증상여대조조상비,차이무통계학의의(P＜0.05).결론 구염청과립여아석락위연합용약능유효완해포진성간구염인기적동통,감소궤양지속천수,시치료포진성간구염적일충유효적치료방법.
OBjective To explore the clinical effect of Kouyanqing combined with acvclovir for herpetic gingivostomatitis.Methods 90 cases with herpetic gingivostomatitis were treated in the department of stomatology of Guangzhou Women and Children's Medical Center during February,2012 to May,2012.The patients were randomly divided into a therapeutic group and a control group.45 for each group.The therapeutic group were treated with Kouyanqing and acyclovir,and the control group with acyclovir only.The clinical efficacies and the adverse reactions of these two groups were recorded and compared.Results 78 patients,40 in the therapeutic group and 38 in the control group,diagnosed with herpetic gingivostomatitis completed the study.The oral lesion period was shorter and the fever and eating and drinking difficulties disappeared earlier in the therapeutic group than in the control group,with statistical differences (P ＜ 0.05).There was no statistical difference in drooling between the two groups.Conclusions Kouyanqing combined with acyclovir can alleviate the pain caused by herpetic gingivostomatitis and is an effective protocol for herpetic gingivostomatitis.