山西中医学院学报
山西中醫學院學報
산서중의학원학보
JOURNAL OF SHANXI COLLEGE OF TRADITIONAL CHINESE MEDICINE
2013年
5期
31-32
,共2页
张海%张力%李钦青%阎文斌%季新燕%刘亚明
張海%張力%李欽青%閻文斌%季新燕%劉亞明
장해%장력%리흠청%염문빈%계신연%류아명
肝宁胶囊%质量标准%斑蝥素%GC
肝寧膠囊%質量標準%斑蝥素%GC
간저효낭%질량표준%반모소%GC
Ganning capsules%quality standard%cantharidin%GC
目的：对肝宁胶囊质量标准进行研究。方法：采用薄层色谱法对处方中的紫草进行定性鉴别；采用气相色谱法对处方中的斑蝥素进行含量测定。结果：在薄层色谱中可检出紫草的特征斑点；斑蝥素在0.0138μg～0.1242μg（r=0.9999）范围内线性关系良好，回收率为98.466%（RSD=1.92%，n=5）。结论：本方法简便可行、重复性好，能有效控制该制剂的质量。
目的：對肝寧膠囊質量標準進行研究。方法：採用薄層色譜法對處方中的紫草進行定性鑒彆；採用氣相色譜法對處方中的斑蝥素進行含量測定。結果：在薄層色譜中可檢齣紫草的特徵斑點；斑蝥素在0.0138μg～0.1242μg（r=0.9999）範圍內線性關繫良好，迴收率為98.466%（RSD=1.92%，n=5）。結論：本方法簡便可行、重複性好，能有效控製該製劑的質量。
목적：대간저효낭질량표준진행연구。방법：채용박층색보법대처방중적자초진행정성감별；채용기상색보법대처방중적반모소진행함량측정。결과：재박층색보중가검출자초적특정반점；반모소재0.0138μg～0.1242μg（r=0.9999）범위내선성관계량호，회수솔위98.466%（RSD=1.92%，n=5）。결론：본방법간편가행、중복성호，능유효공제해제제적질량。
Objective:To study the quality standard for Ganning capsules. Methods:Radix Arnebiae in prescription was i-dentified by TLC,and the content of cantharidin in prescription was detected by HPLC. Results:The characteristic spots of Radix Arnebiae were identified by TLC. Cantharidin showed a good linear relationship at a range of 0.013 8μg~0.124 2μg (r=0.999 9). The average recovery was 98.466%(RSD=1.92%,n=5). Conclution:The methods are available with a good reproducibility and can control the quality of this preparation effectively.
