1,3,4-噻二唑取代的N-（噻吩并吡啶）乙酰胺类化合物的合成及生物活性研究
1,3,4-새이서취대적N-（새분병필정）을선알류화합물적합성급생물활성연구
Synthesis and Biological Activities of N-(thieno[2,3-b]pyridin-3-yl)acetamide Compounds with Substituent of 1,3,4-Thiadiazole
  • 万方数据
    现代农药 현대농약
    MODERN AGROCHEMICALS
    2013年 6期 8-12 ,共5页

    周炳森%欧阳贵平%孔欣欣%郭正美%贺宝安%黎世泽

    주병삼%구양귀평%공흔흔%곽정미%하보안%려세택

    (噻吩并吡啶)乙酰胺%1,3,4-噻二唑%合成%生物活性 (噻吩併吡啶)乙酰胺%1,3,4-噻二唑%閤成%生物活性
    (새분병필정)을선알%1,3,4-새이서%합성%생물활성
    (thieno[2,3-b]pyridin-3-yl)acetamide%1,3,4-thiadiazole%synthesis%bioactivity
    以2-氯-3-氰基吡啶为起始原料，设计并合成了一系列1,3,4-噻二唑取代的N-(噻吩并吡啶)乙酰胺类新化合物。所有化合物或中间体结构经1H NMR、13C NMR、IR和MS确认。初步生物活性测试结果表明，部分化合物具有较高的抑菌或杀虫活性。
    이2-록-3-청기필정위기시원료，설계병합성료일계렬1,3,4-새이서취대적N-(새분병필정)을선알류신화합물。소유화합물혹중간체결구경1H NMR、13C NMR、IR화MS학인。초보생물활성측시결과표명，부분화합물구유교고적억균혹살충활성。
    A series of novel N-(thieno[2,3-b]pyridin-3-yl)acetamide compounds with substituent of 1,3,4-thiadiazole were designed and synthesized starting from 2-chloronicotinonitrile. The structures of all target compounds or intermediates were confirmed by 1H NMR, 13C NMR, IR and MS. The preliminary bioassay results showed that some of the compounds exhibited antifungal&insecticidal activities.
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