CAJ | 학술논문

建立了液相色谱仪测定环氧氯丙烷工业中间体中己二酸含量的方法。样品采用甲醇-10 mmol/L磷酸缓冲液（体积比5∶95）溶液提取，C18固相萃取柱净化，紫外检测器检测，外标法定量。己二酸在100～2000 mg/L范围内线性良好，相关系数大于0.9999，按10S/N计算，己二酸定量限为25.0 mg/kg。添加回收率为91.1%～112.2%，测定结果的相对标准偏差为4.7%～7.9%（n=5）。该方法简单快速，回收率高，重现性好，满足工业分析要求。
건립료액상색보의측정배양록병완공업중간체중기이산함량적방법。양품채용갑순-10 mmol/L린산완충액（체적비5∶95）용액제취，C18고상췌취주정화，자외검측기검측，외표법정량。기이산재100～2000 mg/L범위내선성량호，상관계수대우0.9999，안10S/N계산，기이산정량한위25.0 mg/kg。첨가회수솔위91.1%～112.2%，측정결과적상대표준편차위4.7%～7.9%（n=5）。해방법간단쾌속，회수솔고，중현성호，만족공업분석요구。
A method for determination of adipic acid in epoxy chloropropane industrial intermediates by liquid chromatography was established. The sample was extracted by methanol-10 mmol/L phosphate buffer and cleaned up with C18 solid-phase,then analyzed by UV detector and quantified by the external standard method. Good linear relation was obtained in the range of 100-2 000 mg/L with the correlation coefficient more than 0.999 9,the limit of quantitation was 25.0 mg/kg(10S/N). The recoveries was 91.1%-112.2%with RSD of 4.7%-7.9%(n=5). The method is simple and fast with high recovery rate,good reproducibility,and meets the demand of industrial analysis.