医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2013年
11期
31-32
,共2页
艾迪注射液%CEF方案%乳腺癌
艾迪註射液%CEF方案%乳腺癌
애적주사액%CEF방안%유선암
Addie injection%CEF%breast cancer
目的：观察艾迪注射液配合CEF方案（环磷酰胺、表阿霉素、氟尿嘧啶）治疗乳腺癌患者近期疗效及毒副反应。方法：将52例原发性乳腺癌随机分为2组，治疗组为艾迪注射液配合CEF方案组，对照组为单纯CEF方案组，对2组患者近期疗效、毒副反应及手术后标本的淋巴结转移和C2erbB -2的表达情况进行比较。结果：治疗组总缓解率为90．62％，对照组为75．00％，差异无显著性；治疗组白细胞下降程度及消化道反应轻于对照组（ P ＜0．05），生活质量、体重及肝肾功能的改变有明显差异（ P ＜0．05或 P＜0．01）；治疗组腋窝淋巴结阳性率及乳腺癌C2erbB2表达阳性率分别为31．25％及6．25％，对照组为60％及35％，两组比较有显著性差异（P＜0．05）。结论：艾迪注射液对提高化疗疗效，减轻毒副反应具有一定临床价值。
目的：觀察艾迪註射液配閤CEF方案（環燐酰胺、錶阿黴素、氟尿嘧啶）治療乳腺癌患者近期療效及毒副反應。方法：將52例原髮性乳腺癌隨機分為2組，治療組為艾迪註射液配閤CEF方案組，對照組為單純CEF方案組，對2組患者近期療效、毒副反應及手術後標本的淋巴結轉移和C2erbB -2的錶達情況進行比較。結果：治療組總緩解率為90．62％，對照組為75．00％，差異無顯著性；治療組白細胞下降程度及消化道反應輕于對照組（ P ＜0．05），生活質量、體重及肝腎功能的改變有明顯差異（ P ＜0．05或 P＜0．01）；治療組腋窩淋巴結暘性率及乳腺癌C2erbB2錶達暘性率分彆為31．25％及6．25％，對照組為60％及35％，兩組比較有顯著性差異（P＜0．05）。結論：艾迪註射液對提高化療療效，減輕毒副反應具有一定臨床價值。
목적：관찰애적주사액배합CEF방안（배린선알、표아매소、불뇨밀정）치료유선암환자근기료효급독부반응。방법：장52례원발성유선암수궤분위2조，치료조위애적주사액배합CEF방안조，대조조위단순CEF방안조，대2조환자근기료효、독부반응급수술후표본적림파결전이화C2erbB -2적표체정황진행비교。결과：치료조총완해솔위90．62％，대조조위75．00％，차이무현저성；치료조백세포하강정도급소화도반응경우대조조（ P ＜0．05），생활질량、체중급간신공능적개변유명현차이（ P ＜0．05혹 P＜0．01）；치료조액와림파결양성솔급유선암C2erbB2표체양성솔분별위31．25％급6．25％，대조조위60％급35％，량조비교유현저성차이（P＜0．05）。결론：애적주사액대제고화료료효，감경독부반응구유일정림상개치。
Objective :Observation of Addie injection combined with CEF regimen (cyclophosphamide ,5 -fluorouracil ,epirubicin) the efficacy and toxicity of the treatment of breast cancer patients .Methods :52 cases of primary breast cancer were divided into 2 groups ,the treatment group Addie injection combined with CEF regimen group ,control group ,simple CEF group ,to compare the expression of speci-mens of lymph node metastasis and C2erbB - 2 of the efficacy ,toxicity and 2 patients after operation .Results :in treatment group ,the total response rate was 90 .62% ,75% in the control group ,no significant difference ;the treatment group the decrease of white blood cells and di-gestive tract reaction than that in the control group (P < 0 .05) ,quality of life ,body weight and liver and kidney function changes were sig-nificantly different (P < 0 .05 or P< 0 .01);the treatment group of axillary lymph node positive rate and the positive rate of C 2erbB2 ex-pression in breast cancer were 31 .25% and 6 .25% ,the control group was 60% and 35% ,there were significant difference between two groups (P < 0 .05) .Conclusion :Addie injection to improve the efficacy of chemotherapy ,reduce the toxicity of certain clinical value .
