中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
11期
19-20
,共2页
胆固醇%总胆汁酸%肝功能分级
膽固醇%總膽汁痠%肝功能分級
담고순%총담즙산%간공능분급
Total bile acid%Cholesterol%Liver function
目的：通过联合测定肝病患者血清胆固醇(CHO)与总胆汁酸(TBA)的含量水平，以探讨其临床意义。方法对160例肝病患者按照Child-Pugh肝功能分级法分级后与80例健康者比较血清中CHO与TBA水平。结果肝硬化组和肝癌组血清CHO含量明显低于对照组，而TBA含量明显高于对照组(P<0.01)。CHO在肝硬化组C级中最低，与A级和B级比较差异有统计学意义(P<0.05)， A级和B级比较差异无统计学意义(P>0.05)；TBA在A级、B级和C级各级之间比较差异有统计学意义(P<0.05)，且随着肝功能Child-Pugh分级的增高而增高。结论肝病患者CHO、TBA能敏感反映肝功能及肝硬化的进展情况。
目的：通過聯閤測定肝病患者血清膽固醇(CHO)與總膽汁痠(TBA)的含量水平，以探討其臨床意義。方法對160例肝病患者按照Child-Pugh肝功能分級法分級後與80例健康者比較血清中CHO與TBA水平。結果肝硬化組和肝癌組血清CHO含量明顯低于對照組，而TBA含量明顯高于對照組(P<0.01)。CHO在肝硬化組C級中最低，與A級和B級比較差異有統計學意義(P<0.05)， A級和B級比較差異無統計學意義(P>0.05)；TBA在A級、B級和C級各級之間比較差異有統計學意義(P<0.05)，且隨著肝功能Child-Pugh分級的增高而增高。結論肝病患者CHO、TBA能敏感反映肝功能及肝硬化的進展情況。
목적：통과연합측정간병환자혈청담고순(CHO)여총담즙산(TBA)적함량수평，이탐토기림상의의。방법대160례간병환자안조Child-Pugh간공능분급법분급후여80례건강자비교혈청중CHO여TBA수평。결과간경화조화간암조혈청CHO함량명현저우대조조，이TBA함량명현고우대조조(P<0.01)。CHO재간경화조C급중최저，여A급화B급비교차이유통계학의의(P<0.05)， A급화B급비교차이무통계학의의(P>0.05)；TBA재A급、B급화C급각급지간비교차이유통계학의의(P<0.05)，차수착간공능Child-Pugh분급적증고이증고。결론간병환자CHO、TBA능민감반영간공능급간경화적진전정황。
Objective To evaluate the clinical significance of serum cholesterol (CHO) and total bile acid (TBA) in patients with liver disease. Methods The serum levels of CHO and TBA were prospectively studied in 160 patients with liver disease and 80 healthy persons. Results Serum CHO level was significantly lower in cases with liver cirrhosis and hepatic carcinoma than that of control group (P<0.05), but serum TBA level significantly higher (P<0.01). Serum CHO level was the lowest in Child-Pugh C grade and was significantly different between C grade and A grade as well as B grade (P<0.05). Serum TBA level was significantly different among A, B and C grade, it increased with the liver function of Child-Pugh grade. Conclusion Serum TBA level can sensitively reflect the degree of liver cirrhosis, the tests of TBA and CHO are helpful to confirming the state of patients.
