CAJ | 학술논문

目的：观察手腕部磁共振成像(MRI)分析中西医结合治疗类风湿性关节炎的疗效。方法将临床确诊类风湿性关节炎患者46例分为两组：中西医结合治疗组(21例)和西医对照组(25例)，治疗前、后均进行MRI平扫+增强检查及X线检查，分析比较治疗前后临床效果、MRI及X线影像学改变。结果中西医结合治疗组有效率为95%，西医对照组有效率为72%，两组疗效差异有统计学意义(P<0.05)。治疗后MRI显示增厚的滑膜厚度减小、滑膜及血管翳强化程度减弱、骨髓水肿减轻或消失、关节积液减少、骨和软骨侵蚀无增加。治疗前后的类风湿性关节炎患者X 线检查对比无明显变化。结论中西医结合治疗类风湿性关节炎较单纯西医治疗疗效好。MRI能有效评价类风湿性关节炎治疗效果，临床上可推广应用。
목적：관찰수완부자공진성상(MRI)분석중서의결합치료류풍습성관절염적료효。방법장림상학진류풍습성관절염환자46례분위량조：중서의결합치료조(21례)화서의대조조(25례)，치료전、후균진행MRI평소+증강검사급X선검사，분석비교치료전후림상효과、MRI급X선영상학개변。결과중서의결합치료조유효솔위95%，서의대조조유효솔위72%，량조료효차이유통계학의의(P<0.05)。치료후MRI현시증후적활막후도감소、활막급혈관예강화정도감약、골수수종감경혹소실、관절적액감소、골화연골침식무증가。치료전후적류풍습성관절염환자X 선검사대비무명현변화。결론중서의결합치료류풍습성관절염교단순서의치료료효호。MRI능유효평개류풍습성관절염치료효과，림상상가추엄응용。
Objective Analyze therapeutic effect of combined treatment of traditional Chinese medicine and western medicine for Rheumatoid arthritis(RA)via MRI observation. Methods 46 patients clinically diagnosed as RA were divided into 2 groups:the cooperation of Chinese and Western medicine group (21 cases) and Western medicine control group (25 cases). All patients underwent MRI and X-ray examination before and after treatment. All patients' clinical symptoms, MRI and X-ray examination data were analyzed and compared before and after treatment. Results The cooperation of Chinese and Western medicine group had statistical difference with Western medicine group(P<0.05) , effective rate of the former was 95%, while the latter was 72%. Post-therapy MRI showed that synovial thickness reduced, Synovial and pannus enhancement decreased, bone and cartilage erosion did not increased, marrow edema lessened or vanished, fluid accumulation in joint reduced. There were no obvious changes on X-ray examination before and after treatment. Conclusions The cooperation of Chinese and Western medicine treatment was better than western medicine alone. MRI could effectively assess RA treatment, so clinical promotion might be done.