CAJ | 학술논문

目的：观察温阳通络胶囊合用腰八针温针灸对腰椎间盘突出症患者JOA评分、SOD活性和MDA含量的影响。方法：将120例腰椎间盘突出症患者随机均分为治疗组（温阳通络胶囊配合腰八针温针灸合用组）、对照1组（温阳通络胶囊组）、对照2组（腰八针温针灸组）三组，连续治疗4周后采用改良JOA评分评价其临床疗效，并分别于治疗前后检查空腹血浆SOD、MDA。结果：治疗组临床疗效较对照1组和对照2组均有显著性改善（P<0.05）。治疗后三组血浆SOD活性均较治疗前显著性增高、MDA含量显著性降低（P<0.05），治疗组治疗后SOD活性较对照组1组和对照2组均有显著性增加（P<0.01），而MDA含量有显著性减少（P<0.01）。结论：温阳通络胶囊配合腰八针温针灸是治疗LDH的有效方法之一，可提高患者血浆SOD活性、降低MDA水平，LDH临床疗效好于温阳通络胶囊和腰八针温针灸的单独应用。
목적：관찰온양통락효낭합용요팔침온침구대요추간반돌출증환자JOA평분、SOD활성화MDA함량적영향。방법：장120례요추간반돌출증환자수궤균분위치료조（온양통락효낭배합요팔침온침구합용조）、대조1조（온양통락효낭조）、대조2조（요팔침온침구조）삼조，련속치료4주후채용개량JOA평분평개기림상료효，병분별우치료전후검사공복혈장SOD、MDA。결과：치료조림상료효교대조1조화대조2조균유현저성개선（P<0.05）。치료후삼조혈장SOD활성균교치료전현저성증고、MDA함량현저성강저（P<0.05），치료조치료후SOD활성교대조조1조화대조2조균유현저성증가（P<0.01），이MDA함량유현저성감소（P<0.01）。결론：온양통락효낭배합요팔침온침구시치료LDH적유효방법지일，가제고환자혈장SOD활성、강저MDA수평，LDH림상료효호우온양통락효낭화요팔침온침구적단독응용。
Objective:To observe the influence of Wenyangtongluo capsules combined with warm needling of eight needles on waist for lumbar disc herniation on modified JOA scores, SOD and MDA. Methods:120 patients were randomly divided into treatment group (Wenyangtongluo capsules combined with warm needling of eight needles on waist group), control group 1 (Wenyangtongluo capsules group) and control group 2 (warm nee-dling of eight needles on waist group), used modified JOA scores to evaluate the efficacy after continuous treating for 4 weeks, and checked the fast-ing plasma SOD and MDA before and after treatment. Results:Compared with control group1 and control group 2, the efficacy of treatment group had significantly improved (P<0.05). After treatment, the activity of plasma SOD had significantly increased and the content of MDA had significant-ly decreased (P<0.05);compared with control group1 and control group 2, the activity of SOD of treatment group that after the treatment had signifi-cantly increased (P<0.01) and MDA had significantly decreased (P<0.01). Conclusion:Wenyangtongluo capsules combined with warm needling of eight needles on waist is one of the effective ways to treat lumbar disc herniation, it can improve the activity of plasma SOD and reduce the level of MDA, and the efficacy is better than separately using Wenyangtongluo capsules or warm needling of eight needles on waist.