中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2013年
22期
187-188,190
,共3页
翼状胬肉%角膜缘干细胞移植术%生物羊膜移植术%复发%并发症
翼狀胬肉%角膜緣榦細胞移植術%生物羊膜移植術%複髮%併髮癥
익상노육%각막연간세포이식술%생물양막이식술%복발%병발증
Pterygium%Limbal stem cell transplantation%Biological amniotic membrane transplantation%Recurrence%Complications
目的：探讨角膜缘干细胞移植术治疗翼状胬肉的手术效果，为进一步提高翼状胬肉治疗方法的选择提供参考依据。方法选择2012年1月～2013年1月在我院行手术治疗的翼状胬肉患者74例，74眼，入选病例中应用角膜缘干细胞移植术38例，设立为研究组，其余36例行生物羊膜移植术，设立为对照组，观察比较两组患者角膜创面上皮愈合时间、比较两组患者术前术后裸眼视力及术后随访其复发率、并发症。结果研究组患者角膜创面上皮愈合时间明显快于对照组，组间比较，差异具有统计学意义（P＜0.05）。研究组患者术后复发率2.6%，显著低于对照组（P＜0.05）。研究组和对照组患者术后3周其裸眼视力均分别较术前明显提高，且研究组患者术后3周其裸眼视力改善更显著，组间比较，差异具有统计学意义（P＜0.05）。结论角膜缘干细胞移植术治疗翼状胬肉具有愈合快、并发症少、复发率低等优点，值得基层医院广泛推广和应用。
目的：探討角膜緣榦細胞移植術治療翼狀胬肉的手術效果，為進一步提高翼狀胬肉治療方法的選擇提供參攷依據。方法選擇2012年1月～2013年1月在我院行手術治療的翼狀胬肉患者74例，74眼，入選病例中應用角膜緣榦細胞移植術38例，設立為研究組，其餘36例行生物羊膜移植術，設立為對照組，觀察比較兩組患者角膜創麵上皮愈閤時間、比較兩組患者術前術後裸眼視力及術後隨訪其複髮率、併髮癥。結果研究組患者角膜創麵上皮愈閤時間明顯快于對照組，組間比較，差異具有統計學意義（P＜0.05）。研究組患者術後複髮率2.6%，顯著低于對照組（P＜0.05）。研究組和對照組患者術後3週其裸眼視力均分彆較術前明顯提高，且研究組患者術後3週其裸眼視力改善更顯著，組間比較，差異具有統計學意義（P＜0.05）。結論角膜緣榦細胞移植術治療翼狀胬肉具有愈閤快、併髮癥少、複髮率低等優點，值得基層醫院廣汎推廣和應用。
목적：탐토각막연간세포이식술치료익상노육적수술효과，위진일보제고익상노육치료방법적선택제공삼고의거。방법선택2012년1월～2013년1월재아원행수술치료적익상노육환자74례，74안，입선병례중응용각막연간세포이식술38례，설립위연구조，기여36례행생물양막이식술，설립위대조조，관찰비교량조환자각막창면상피유합시간、비교량조환자술전술후라안시력급술후수방기복발솔、병발증。결과연구조환자각막창면상피유합시간명현쾌우대조조，조간비교，차이구유통계학의의（P＜0.05）。연구조환자술후복발솔2.6%，현저저우대조조（P＜0.05）。연구조화대조조환자술후3주기라안시력균분별교술전명현제고，차연구조환자술후3주기라안시력개선경현저，조간비교，차이구유통계학의의（P＜0.05）。결론각막연간세포이식술치료익상노육구유유합쾌、병발증소、복발솔저등우점，치득기층의원엄범추엄화응용。
Objective To investigate the effect of limbal stem cell transplantation in treatment of pterygium surgery, in order to further provide reference for improving the pterygium. Methods 74 cases of pterygium(74 eyes)from January 2012 to January 2013 in our hospital were selected as the observation subjects, the 38 patients adopted limbal stem cell lines grafting as study group, the 36 patients adopted amniotic membrane transplantation as control group. The corneal epithelial wound healing time,preoperative and postoperative visual acuity and postoperative follow-up the recurrence rate, complications were observed and compared between two groups. Results The corneal epithelial wound healing time of the study group was significantly faster than the control group, the difference was statistically significant(P < 0.05).The recurrence rate of study group was 2.6%,was significantly lower than the control group (P<0.05).After treatment three weeks,uncorrected visual acuity of study group and the control group significantly improved than the preoperative and postoperative,and the study group improved more significant than the control group, the difference was statistically significant(P<0.05). Conclusion Limbal stem cell transplantation in treatment of pterygium with faster healing have fewer complications,low recurrence rate, etc. It is worth of the primary hospital and applied widely.
