CAJ | 학술논문

目的：分析干化学法和湿化学法测定血糖的相关程度，探讨两种方法能否共用同一参考区间，保持检测结果的一致性。方法依据美国临床实验室标准化协会的EP9-A2文件，以ADVIA2400生化仪组成的检测系统作为比较方法，以VITROS FS 5．1生化仪组成的检测系统作为实验方法，分析两种方法之间的相关性，换算所得直线回归方程的斜率、截距作为干化学仪的校正参数，再重复测定血糖，分析参数改变前后两种方法的相关性和临床可接受性。结果参数改变前，两种方法检测血糖相关性很好，相关系数 r2＝0．9995，但是不同医学决定水平的系统误差均大于允许偏差（EA）的1/2，校正参数后，两种方法检测血糖 r2＝0．9997，SE均小于EA 的1/2。结论干化学法和湿化学法测定血糖浓度相关性良好，通过校正参数后可共用同一参考区间，其检测结果临床可接受。
목적：분석간화학법화습화학법측정혈당적상관정도，탐토량충방법능부공용동일삼고구간，보지검측결과적일치성。방법의거미국림상실험실표준화협회적EP9-A2문건，이ADVIA2400생화의조성적검측계통작위비교방법，이VITROS FS 5．1생화의조성적검측계통작위실험방법，분석량충방법지간적상관성，환산소득직선회귀방정적사솔、절거작위간화학의적교정삼수，재중복측정혈당，분석삼수개변전후량충방법적상관성화림상가접수성。결과삼수개변전，량충방법검측혈당상관성흔호，상관계수 r2＝0．9995，단시불동의학결정수평적계통오차균대우윤허편차（EA）적1/2，교정삼수후，량충방법검측혈당 r2＝0．9997，SE균소우EA 적1/2。결론간화학법화습화학법측정혈당농도상관성량호，통과교정삼수후가공용동일삼고구간，기검측결과림상가접수。
Objective To study the correlation of blood glucose results by dry chemical and liquid chemical a-nalysis ,explore whether these two methods can share a reference interval ,while keep the result consistency . Methods According to EP9-A document request of National Committee for Clinical Laboratory of Standards ,the comparative method(X) was ADVIA2400 ,VITROS FS 5 .1 examination method(Y) ,analyze the correlation between the two methods .Detected the blood sugar level again by these two methods after the dry chemical analysis parame-ters were changed .Results Before changes in the parameters ,the blood sugar level by the two methods correlated well(r2 =0 .999 5) ,however the expected bias(SE) of the different Medicine decide level was greater than the allowa-ble deviation (EA/2 ) .After parameters calibration ,these two methods of blood sugar correlated well too ( r2 =0 .999 7) ,SE was less than EA/2 .Conclusion Dry chemical and liquid chemical analysis have good correlation in blood sugar concentration ,they can share the same reference interval after parameters calibration ,which can be re-ceived in clinic .