检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2013年
24期
3293-3294
,共2页
空腹血糖%糖化血红蛋白%糖尿病%筛查
空腹血糖%糖化血紅蛋白%糖尿病%篩查
공복혈당%당화혈홍단백%당뇨병%사사
fasting blood glucose%glycosylated hemoglobin%diabete%screening
目的：探讨空腹血糖（FPG）与糖化血红蛋白（HbA1C）联合检测筛查糖尿病的临床价值。方法选取糖尿病高危人群8634例，抽取空腹静脉血，使用全自动生化仪对FPG和HbA1C水平进行检测。结果 FPG阳性率为8．61％，HbA1C阳性率为7．20％，2项分别进行筛查阳性率差异无统计学意义（P＞0．05）。 FPG 联合HbA1C进行筛查，其中一项及以上为阳性者共941例，占10．90％，明显高于 FPG 阳性、HbA1C阳性或阴性及FPG阳性或阴性、HbA1C阳性两种情况者，差异有统计学意义（P＜0．05）。分别有319例（3．69％）和198例（2．29％）患者仅FPG或HbA1C阳性，明显少于FPG阳性或HbA1C阳性。按照体检人群FPG水平将其分为在年龄和体质量方面有可比性的3组。与FPG＜6．1 mmol/L相比，FPG为6．1～6．9 mmol/L组FPG和 HbA1C水平均有明显升高，且差异有统计学意义（P＜0．05）；FPG＞6．9 mmol/L组FPG和 HbA1C平均水平明显高于 FPG＜6．1 mmol/L、FPG为6．1～6．9 mmol/L两组，差异有统计学意义（P＜0．05）。2项指标呈正相关。结论采用FPG与HbA1C筛查糖尿病具有一定的漏诊率，将2项联合检测，可以降低漏诊率，提高检出率，有重要的临床意义。
目的：探討空腹血糖（FPG）與糖化血紅蛋白（HbA1C）聯閤檢測篩查糖尿病的臨床價值。方法選取糖尿病高危人群8634例，抽取空腹靜脈血，使用全自動生化儀對FPG和HbA1C水平進行檢測。結果 FPG暘性率為8．61％，HbA1C暘性率為7．20％，2項分彆進行篩查暘性率差異無統計學意義（P＞0．05）。 FPG 聯閤HbA1C進行篩查，其中一項及以上為暘性者共941例，佔10．90％，明顯高于 FPG 暘性、HbA1C暘性或陰性及FPG暘性或陰性、HbA1C暘性兩種情況者，差異有統計學意義（P＜0．05）。分彆有319例（3．69％）和198例（2．29％）患者僅FPG或HbA1C暘性，明顯少于FPG暘性或HbA1C暘性。按照體檢人群FPG水平將其分為在年齡和體質量方麵有可比性的3組。與FPG＜6．1 mmol/L相比，FPG為6．1～6．9 mmol/L組FPG和 HbA1C水平均有明顯升高，且差異有統計學意義（P＜0．05）；FPG＞6．9 mmol/L組FPG和 HbA1C平均水平明顯高于 FPG＜6．1 mmol/L、FPG為6．1～6．9 mmol/L兩組，差異有統計學意義（P＜0．05）。2項指標呈正相關。結論採用FPG與HbA1C篩查糖尿病具有一定的漏診率，將2項聯閤檢測，可以降低漏診率，提高檢齣率，有重要的臨床意義。
목적：탐토공복혈당（FPG）여당화혈홍단백（HbA1C）연합검측사사당뇨병적림상개치。방법선취당뇨병고위인군8634례，추취공복정맥혈，사용전자동생화의대FPG화HbA1C수평진행검측。결과 FPG양성솔위8．61％，HbA1C양성솔위7．20％，2항분별진행사사양성솔차이무통계학의의（P＞0．05）。 FPG 연합HbA1C진행사사，기중일항급이상위양성자공941례，점10．90％，명현고우 FPG 양성、HbA1C양성혹음성급FPG양성혹음성、HbA1C양성량충정황자，차이유통계학의의（P＜0．05）。분별유319례（3．69％）화198례（2．29％）환자부FPG혹HbA1C양성，명현소우FPG양성혹HbA1C양성。안조체검인군FPG수평장기분위재년령화체질량방면유가비성적3조。여FPG＜6．1 mmol/L상비，FPG위6．1～6．9 mmol/L조FPG화 HbA1C수평균유명현승고，차차이유통계학의의（P＜0．05）；FPG＞6．9 mmol/L조FPG화 HbA1C평균수평명현고우 FPG＜6．1 mmol/L、FPG위6．1～6．9 mmol/L량조，차이유통계학의의（P＜0．05）。2항지표정정상관。결론채용FPG여HbA1C사사당뇨병구유일정적루진솔，장2항연합검측，가이강저루진솔，제고검출솔，유중요적림상의의。
Objective To investigate the clinical value of fasting blood glucose (FPG) and glycosylated hemo-globin joint detection for screening diabetes .Methods 8 634 cases at high risk of diabetes were collected ,then detec-ted their fasting venous blood .Automatic biochemical analyzer was used to detect the FPG and HbA1C levels . Results FPG positive rate was 8 .61% ,the HbA1c positive rate was 7 .20% ,the difference between two methods for screening was not significant(P>0 .05) .The FPG united HbA1c screening one and above was positive in a total of 941 cases ,accounting for 10 .90% ,Significantly higher than the FPG positive ,HbA1C positive or negative and FPG positive or negative ,HbA1C positive (P<0 .05) .319 cases(3 .69% ) and 198 cases(2 .29% ) patients with FPG or HbA1c only positive was Significantly less than the FPG or HbA1C positive .According to the levels of FPG ,physi-cal examination population were divided into comparability of the three groups in terms of age and body mass .Com-pared with FPG<6 .1 mmol/L ,the group of FPG 6 .1 -6 .9 mmol/L HbA1c and FPG levels were significantly in-creased(P<0 .05);the group of FPG >6 .9 mmol/L FPG levels were significantly higher than the other two groups (P<0 .05) .There was a positive correlation between the two indicators .Conclusion The FPG and HbA1C screening for diabetes has a certain rate of misdiagnosis ,the two inspection methods in combination could reduce the rate of misdiagnosis and improve the detection rate has important clinical significance .
