检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2013年
24期
3253-3254,3257
,共3页
缺血性脑卒中%认知障碍%危险因素
缺血性腦卒中%認知障礙%危險因素
결혈성뇌졸중%인지장애%위험인소
ischemic stroke%cognitive impairment%risk factor
目的：分析缺血性脑卒中后形成血管性认知障碍（VCI）的危险因素。方法选取开县人民医院神经内科2011年8月至2012年6月住院确诊为缺血性脑卒中的176例患者，对其可能发生的VCI危险因素进行统计分析。结果 VCI的发生与性别、吸烟史、饮酒史、冠心病、高血压等均无相关性（ P＞0．05），与年龄、糖尿病、白质疏松症有显著相关性（P＜0．01）；VCI的发病与脑卒中的发病次数、发病部位、发病面积均有相关性。其中脑卒中发病次数超过2次的患者VCI发病率（66．7％）明显高于少于或等于2次的发病率（35．7％），差异有统计学意义（P＜0．01）；大面积脑卒中患者VCI发病率（66．7％）明显高于小面积脑卒中患者发病率（8．2％），差异有统计学意义（P＜0．01）；发病部位为额、顶、颞、枕和丘脑的患者VCI发病率（74．3％、47．9％、67．4％、42．9％、60．0％）明显高于基底核患者发病率（24．3％），差异有统计学意义（P＜0．01）。结论缺血性脑卒中后VCI与发病次数、卒中面积、病灶部位、糖尿病、白质疏松症等多种因素有关，患者如有上述危险因素易发生VCI ，应及早予以防治。
目的：分析缺血性腦卒中後形成血管性認知障礙（VCI）的危險因素。方法選取開縣人民醫院神經內科2011年8月至2012年6月住院確診為缺血性腦卒中的176例患者，對其可能髮生的VCI危險因素進行統計分析。結果 VCI的髮生與性彆、吸煙史、飲酒史、冠心病、高血壓等均無相關性（ P＞0．05），與年齡、糖尿病、白質疏鬆癥有顯著相關性（P＜0．01）；VCI的髮病與腦卒中的髮病次數、髮病部位、髮病麵積均有相關性。其中腦卒中髮病次數超過2次的患者VCI髮病率（66．7％）明顯高于少于或等于2次的髮病率（35．7％），差異有統計學意義（P＜0．01）；大麵積腦卒中患者VCI髮病率（66．7％）明顯高于小麵積腦卒中患者髮病率（8．2％），差異有統計學意義（P＜0．01）；髮病部位為額、頂、顳、枕和丘腦的患者VCI髮病率（74．3％、47．9％、67．4％、42．9％、60．0％）明顯高于基底覈患者髮病率（24．3％），差異有統計學意義（P＜0．01）。結論缺血性腦卒中後VCI與髮病次數、卒中麵積、病竈部位、糖尿病、白質疏鬆癥等多種因素有關，患者如有上述危險因素易髮生VCI ，應及早予以防治。
목적：분석결혈성뇌졸중후형성혈관성인지장애（VCI）적위험인소。방법선취개현인민의원신경내과2011년8월지2012년6월주원학진위결혈성뇌졸중적176례환자，대기가능발생적VCI위험인소진행통계분석。결과 VCI적발생여성별、흡연사、음주사、관심병、고혈압등균무상관성（ P＞0．05），여년령、당뇨병、백질소송증유현저상관성（P＜0．01）；VCI적발병여뇌졸중적발병차수、발병부위、발병면적균유상관성。기중뇌졸중발병차수초과2차적환자VCI발병솔（66．7％）명현고우소우혹등우2차적발병솔（35．7％），차이유통계학의의（P＜0．01）；대면적뇌졸중환자VCI발병솔（66．7％）명현고우소면적뇌졸중환자발병솔（8．2％），차이유통계학의의（P＜0．01）；발병부위위액、정、섭、침화구뇌적환자VCI발병솔（74．3％、47．9％、67．4％、42．9％、60．0％）명현고우기저핵환자발병솔（24．3％），차이유통계학의의（P＜0．01）。결론결혈성뇌졸중후VCI여발병차수、졸중면적、병조부위、당뇨병、백질소송증등다충인소유관，환자여유상술위험인소역발생VCI ，응급조여이방치。
Objective To analyze risk factors for vascular cognitive impairment (VCI) after ischemic stroke . Methods One hundred and seventy-six patients with ischemic stroke from Aug .2011 to Jun .2012 were selected , risk factors of vascular cognitive impairment were anlyzed .Results There was no correlation between VCI and gen-der ,smoking history ,drinking history ,coronary heart disease ,high blood pressure(P>0 .05) ,there was a significant correlation with age ,diabetes mellitus ,leukoaraiosis(P<0 .01);The incidence of VCI and stroke incidence ,onset lo-cation ,incidence area were correlated with .Among them ,the probability of 66 .7% stroke patients with VCI more than 2 times the incidence was significantly higher than that of ≤ 2 was 35 .7% (P<0 .01) ,the difference was signif-icant ;The probability of large area VCI in stroke patients was significantly higher than that in the small area for 66 .7% patients with stroke incidence(8 .2% )(P<0 .01) ,the difference was significant ;the incidence probability po-sition for frontal ,top ,temporal ,occipital and thalamus in patients with VCI (74 .3% ,47 .9% ,67 .4% ,42 .9% , 60 .0% ) was significantly higher than that of substrate nuclear patients (24 .3% )(P<0 .01) ,the difference was sig-nificant .Conclusion VCI is related with the times ,incidence of stroke lesion area ,diabetes ,leukoaraiosis and other factors of ischemic stroke ,patients with these risk factors should be prevented to avoid vascular cognitive impairment as soon as possible .
