CAJ | 학술논문

目的：观察免疫核糖核酸II（BP素）对中晚期肺癌，胃癌及肝癌患者近期疗效及生活质量的影响。方法根据患者能力及要求分别为单纯化疗组，单纯BP组，BP素联合化疗组，分析治疗疗效，并通过Karnofsky评分了解患者生活质量。结果三种中晚期癌症患者中单纯化疗组与单纯应用BP素组无显著性差异P＞0.05。而BP素联合化疗组稳定率明显高于化疗组及BP素组，以肺癌，胃癌为主，分别具有统计学意义P＜0.05。三种中晚期癌应用BP素及BP素联合化疗组的生活质量分别明显高于化疗组P＜0.05。结论 BP素是一种高效，低毒的生物调节剂，具有抑制肿瘤细胞，增强化疗疗效，减少副反应提高生存质量的作用。
목적：관찰면역핵당핵산II（BP소）대중만기폐암，위암급간암환자근기료효급생활질량적영향。방법근거환자능력급요구분별위단순화료조，단순BP조，BP소연합화료조，분석치료료효，병통과Karnofsky평분료해환자생활질량。결과삼충중만기암증환자중단순화료조여단순응용BP소조무현저성차이P＞0.05。이BP소연합화료조은정솔명현고우화료조급BP소조，이폐암，위암위주，분별구유통계학의의P＜0.05。삼충중만기암응용BP소급BP소연합화료조적생활질량분별명현고우화료조P＜0.05。결론 BP소시일충고효，저독적생물조절제，구유억제종류세포，증강화료료효，감소부반응제고생존질량적작용。
Objective To evaluated the therapeutic effect of BP on patients with median advanced lung cancer, stomach cancer and liver cancer. Methods 123 cases of malignant tumors were divided into three groups. Those are regular chemotherapy, BP and BP in combination with chemotherapy. Results There was no signiifcance between the group of chemotherapy and the BP in median advanced cancer(P>0.05).The effective of BP combined with chemotherapy was much better than the chemotherapy and BP, especially in lung cancer and stomach cancer respectively(P<0.05).And the use of BP can improve the life quality of the patients respectively(P<0.05).Conclusion BP combined with chemotherapy can reduce the side reactions of chemotherapy and improve the effect of treatment.