中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
33期
33-34
,共2页
李厚洋%蔡其辉%田宏现%吴开慧
李厚洋%蔡其輝%田宏現%吳開慧
리후양%채기휘%전굉현%오개혜
缩泉胶囊%高效液相色谱法%乌药醚内酯
縮泉膠囊%高效液相色譜法%烏藥醚內酯
축천효낭%고효액상색보법%오약미내지
Suoquan%Capsules%HPLC%Linderane
目的：建立采用高效液相色谱法测定缩泉胶囊中乌药醚内酯含量的方法。方法采用Shimadzu高效液相色谱仪，C18色谱柱；流动相为乙腈：水（56∶44），检测波长为235nm，流速为1.0mL/min。结果乌药醚内酯在4.8~10.8μg范围内，呈现出良好的线形关系， r=0.9998；平均回收率98.2%，RSD为0.88%（n=5）。结论本方法操作简单易行，专属性强，准确可靠，可用于缩泉胶囊的质量控制。
目的：建立採用高效液相色譜法測定縮泉膠囊中烏藥醚內酯含量的方法。方法採用Shimadzu高效液相色譜儀，C18色譜柱；流動相為乙腈：水（56∶44），檢測波長為235nm，流速為1.0mL/min。結果烏藥醚內酯在4.8~10.8μg範圍內，呈現齣良好的線形關繫， r=0.9998；平均迴收率98.2%，RSD為0.88%（n=5）。結論本方法操作簡單易行，專屬性彊，準確可靠，可用于縮泉膠囊的質量控製。
목적：건립채용고효액상색보법측정축천효낭중오약미내지함량적방법。방법채용Shimadzu고효액상색보의，C18색보주；류동상위을정：수（56∶44），검측파장위235nm，류속위1.0mL/min。결과오약미내지재4.8~10.8μg범위내，정현출량호적선형관계， r=0.9998；평균회수솔98.2%，RSD위0.88%（n=5）。결론본방법조작간단역행，전속성강，준학가고，가용우축천효낭적질량공제。
Objective HPLC methods were established for the determination linderane of Suoquan capsules. Methods The separation was performed on a Shimadzu HPLC, C18 chromatography column;The mobile phase was composed of acetonitrile-water (56∶44);The lfowrate was 1.0mL/min;The detection wavelenth was 235nm. Results There is a good linear relationship within the rang of 4.8~10.8μg, r=0.9998;The average recovery was 98.2%;RSD=0.88%. Conclusions This method is simple, reproducible, accurate and reliable, and can be used for quality control of Suoquan capsule.
