CAJ | 학술논문

目的：比较利福平注射液和利福平胶囊治疗肺结核的临床疗效。方法120例肺结核患者随机分为观察组和对照组各60例，两组患者均采用2 HRZE/4 HR 标准化疗方案治疗，并分别给予利福平注射液、利福平胶囊。结果疗程结束时观察组和对照组痰菌阴转率分别为91.7%、78.3%；病灶吸收率分别为86.7%、61.7%，组间比较差异有统计学意义（P＜0.05或0.01）。两组空洞闭合、缩小例数及不良反应发生率比较差异无统计学意义（P＞0.05）。结论利福平注射液治疗肺结核疗效显著，副作用小，有较好的临床应用价值。
목적：비교리복평주사액화리복평효낭치료폐결핵적림상료효。방법120례폐결핵환자수궤분위관찰조화대조조각60례，량조환자균채용2 HRZE/4 HR 표준화료방안치료，병분별급여리복평주사액、리복평효낭。결과료정결속시관찰조화대조조담균음전솔분별위91.7%、78.3%；병조흡수솔분별위86.7%、61.7%，조간비교차이유통계학의의（P＜0.05혹0.01）。량조공동폐합、축소례수급불량반응발생솔비교차이무통계학의의（P＞0.05）。결론리복평주사액치료폐결핵료효현저，부작용소，유교호적림상응용개치。
Objective To observed and compared the clinical effectiveness of pulmonary tuberculosis curing by rifampicin injection and rifampicin caps. Methods 120 cases of pulmonary tuberculosis patients were divided into the observation group(n=60) and the control group(n=60), all the cases were treated with 2 HREZ/4 HRE standard chemotherapy formula. The observation group were treated by rifampicin injection during the intensify phase, while the control group were treated by taking rifampicin capsules. Results The sputum negative conversion rates were 91.7%and 78.3%in the observation group and the control group respectively, and the lesions absorption rates of 2 groups were 86.7%and 61.7%respectively. It has signiifcant difference between two groups(P<0.05 or 0.01). It has no signiifcant difference between two groups with the hole closed and narrow cases, incidence of adverse reactions. Conclusion Rifampicin injection has a good curative effect in treating pulmonary tuberculosis, which fewer adverse reactions. It is of great value in the clinical practice.