CAJ | 학술논문

目的：通过测定血小板相关参数即血小板计数（PLT）、血小板体积（MPV）、血小板分布宽度（PDW）、D-二聚体（D-D）和超敏-C反应蛋白（Hs-CRP）的水平探讨其与脑梗死的相关性。方法测定64例脑梗死患者和62例健康体检者PLT、MPV、PDW、D-D和Hs-CRP的水平。结果脑梗死患者血浆MPV、PDW、D-D、Hs-CRP水平明显高于对照组（P＜0.01），PLT明显降低（P＜0.01），差异有显著性且MPV、PDW、DD、Hs-CRP的浓度变化随脑梗死面积增加而增加，PLT则降低。结论 PLT、MPV、PDW、D-D和Hs-CRP的水平变化与脑梗死发生发展密切相关，动态监测PLT、MPV、PDW、D-D和Hs-CRP的水平变化在脑梗死患者的诊疗过程中有着重要的临床意义。
목적：통과측정혈소판상관삼수즉혈소판계수（PLT）、혈소판체적（MPV）、혈소판분포관도（PDW）、D-이취체（D-D）화초민-C반응단백（Hs-CRP）적수평탐토기여뇌경사적상관성。방법측정64례뇌경사환자화62례건강체검자PLT、MPV、PDW、D-D화Hs-CRP적수평。결과뇌경사환자혈장MPV、PDW、D-D、Hs-CRP수평명현고우대조조（P＜0.01），PLT명현강저（P＜0.01），차이유현저성차MPV、PDW、DD、Hs-CRP적농도변화수뇌경사면적증가이증가，PLT칙강저。결론 PLT、MPV、PDW、D-D화Hs-CRP적수평변화여뇌경사발생발전밀절상관，동태감측PLT、MPV、PDW、D-D화Hs-CRP적수평변화재뇌경사환자적진료과정중유착중요적림상의의。
Objective Determination of platelet parameters by the platelet count (PLT), platelet volume (MPV),platelet distribution width (PDW), D-dimer (D-D) and hypersensitive c-reactive protein (Hs CRP levels to explore its correlation with cerebral infarction. Methods Determination of 64 cases of patients with cerebral infarction and 62 healthy check-up PLT,MPV,PDW,D-D and Hs CRP levels. Results Cerebral infarction patients plasma MPV,PDW,D-D,Hs CRP levels are signiifcantly higher than control group (P<0.01), PLT decreased obviously (P<0.01), there are signiifcant difference and MPV, PDW, DD, Hs-the concentration of CRP changes increase with the increase of cerebral infarction area,PLT is lower. Conclusion PLT,MPV,PDW,D-D and Hs-change of CRP level is closely related to the development of cerebral infarction,dynamic monitoring of the PLT,MPV,PDW and Hs-,D-D CRP levels in the process of change in the diagnosis and treatment of patients with cerebral infarction has important clinical signiifcance.