CAJ | 학술논문

目的分析高通量透析方式对维持性血液透析（MHD）患者的钙、磷代谢功能影响。方法选取2007年11月-2012年11月惠州市惠阳区人民医院收治的MHD患者70例，分为两组。观察组采用高通量方式透析，对照组采用低通量方式透析，对比两组透析前和透析1、6、12个月后的血钙、血磷水平及Scr（血肌酐）、ALB（血清白蛋白）和PHT（甲状旁腺腺激素）水平变化情况。结果透析前，两组在血钙、血磷水平及Scr、ALB和PHT水平上均无显著差别（P＞0.05）；透析后，观察组患者血钙水平升高更明显，血磷水平降低更明显；同时Scr、ALB和PHT的变化均更明显（P＜0.05）。结论高通量透析方式对MHD患者的钙、磷代谢功能改善效果更显著，透析更为安全有效，值得推广应用。
목적분석고통량투석방식대유지성혈액투석（MHD）환자적개、린대사공능영향。방법선취2007년11월-2012년11월혜주시혜양구인민의원수치적MHD환자70례，분위량조。관찰조채용고통량방식투석，대조조채용저통량방식투석，대비량조투석전화투석1、6、12개월후적혈개、혈린수평급Scr（혈기항）、ALB（혈청백단백）화PHT（갑상방선선격소）수평변화정황。결과투석전，량조재혈개、혈린수평급Scr、ALB화PHT수평상균무현저차별（P＞0.05）；투석후，관찰조환자혈개수평승고경명현，혈린수평강저경명현；동시Scr、ALB화PHT적변화균경명현（P＜0.05）。결론고통량투석방식대MHD환자적개、린대사공능개선효과경현저，투석경위안전유효，치득추엄응용。
Objective To analyse the effects of high lfux hemodialysis in calcium, phosphorus metabolic of patients cured by maintenance hemodialysis dialysis.Methods 70 cases of MHD patients were selected and divided into two groups, the patients of the observation group patients dialysed with high flux method,the patients of the observation group patients dialysed with low flux method,then compared the level of blood calcium、blood phosphorus、Scr、ALBand PHT of the two groups before dialysis and 1、6、12 months after dialysis.Results Before dialysis,there had no signiifcant difference between the two groups on the level of blood calcium、blood phosphorus、Scr、ALBand PHT;After dialysis,the level of blood calcium of the observation group rised more apparently,and the level of blood phosphorus reduced more obviously;At the same time,the level of Scr、ALBand PHT of the observation group all changed more obviously(P<0.05).Conclusion The improving effect of calcium and phosphorus metabolism of maintenance hemodialysis dialysis patients used high lfux dialysis method is more obvious and more safe and effective, the clinicalca applicate widely.