CAJ | 학술논문

目的：探讨发展性照顾对早产儿胃肠、免疫功能成熟度的影响。方法将100例早产儿按随机数字表法分为常规组、观察组各50例，两组均采用常规治疗护理措施，常规组在不能经口喂养期间给予非营养性吸吮，观察组给予发展性照顾，选取40例同期出生的足月儿为对照组，比较观察组和常规组早产儿血胃泌素（ GAS）、恢复出生体重所需时间、院内感染发生率，并比较早产儿与对照组IgM、IgG水平。结果出生时两组 GAS比较，差异无统计学意义（ P＞0．05）；出生5 d常规组早产儿GAS为（115．59±25．87）ng/L，低于观察组的（138．52±26．62）ng/L，差异有统计学意义（t＝4．37，P＜0．01）；出生10 d常规组早产儿IgG、IgM分别为（83．56±21．17），（1．54±0．62） Ug/ml，观察组分别为（91．19±21．29），（1．78±0．62）Ug/ml，两组比较差异无统计学意义（t分别为1．80，1．93；P＞0．05）；观察组恢复出生体重所需时间为（9．12±2．1）d，少于常规组的（12．00±2．12）d，差异有统计学意义（t＝6．68，P＜0．01）；观察组院内感染发生率为0．98‰，常规组为3．94‰，差异无统计学意义（χ2＝0．84，P＞0．01）。结论发展性照顾可促进早产儿胃泌素的释放，促进胃肠功能成熟及体重增长，但短期对免疫功能无明显促进作用。
목적：탐토발전성조고대조산인위장、면역공능성숙도적영향。방법장100례조산인안수궤수자표법분위상규조、관찰조각50례，량조균채용상규치료호리조시，상규조재불능경구위양기간급여비영양성흡전，관찰조급여발전성조고，선취40례동기출생적족월인위대조조，비교관찰조화상규조조산인혈위비소（ GAS）、회복출생체중소수시간、원내감염발생솔，병비교조산인여대조조IgM、IgG수평。결과출생시량조 GAS비교，차이무통계학의의（ P＞0．05）；출생5 d상규조조산인GAS위（115．59±25．87）ng/L，저우관찰조적（138．52±26．62）ng/L，차이유통계학의의（t＝4．37，P＜0．01）；출생10 d상규조조산인IgG、IgM분별위（83．56±21．17），（1．54±0．62） Ug/ml，관찰조분별위（91．19±21．29），（1．78±0．62）Ug/ml，량조비교차이무통계학의의（t분별위1．80，1．93；P＞0．05）；관찰조회복출생체중소수시간위（9．12±2．1）d，소우상규조적（12．00±2．12）d，차이유통계학의의（t＝6．68，P＜0．01）；관찰조원내감염발생솔위0．98‰，상규조위3．94‰，차이무통계학의의（χ2＝0．84，P＞0．01）。결론발전성조고가촉진조산인위비소적석방，촉진위장공능성숙급체중증장，단단기대면역공능무명현촉진작용。
Objective To explore the effect of development care on promoting the maturity of gastrointestinal and immunologic function in the premature infants .Methods One hundred premature infants were randomly divided into the conventional group and the experimental group according to the random number table, each with 50 cases.The two groups received the routine nursing measures , and the conventional group received the non-nutritive sucking during the non-oral feeding period , while the experimental group received development care .The levels of gastrin ( GAS) , IgG and IgM were compared between two groups , and the time required for recovery of birth weight and the incidence rate of nosocomial infection were also compared . Results No difference was found in the level of blood GAS at the birth (P>0.05).The level of GAS in the conventional group was (115.59 ±25.87) ng/L five days after the birth, and was lower than (138.52 ± 26.62)ng/L in the experimental group, and the difference was statistically significant (t=4.37, P<0.01). The levels of IgG and IgM in the conventional group were respectively (83.56 ±21.17) and (1.54 ±0.62)Ug/ml ten days after the birth, and were respectively (91.19 ±21.29) and (1.78 ±0.62) Ug/ml in the experimental group, and the difference was not statistically significant (t =1.80, 1.93, respectively; P >0.05).The time required for recovery of birth weight in the experimental group was (9.12 ±2.1) d, and was less than (12.00 ±2.12) d in the conventional group , and the difference was statistically significant ( t =6.68, P<0.05).The incidence rate of nosocomial infection was 0.98‰ in the experimental group, and was 3.94‰ in the conventional group, and there was no statistically significant difference (χ2 =0.84, P >0.05 ). Conclusions Development care can promote the release of gastrointestinal hormones in premature infants , and also promote the maturity of gastrointestinal function and the increase in weight growth , and has no obvious role in promoting the maturity of immunologic function .