中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2013年
36期
114-115,116
,共3页
慢性阻塞性肺疾病%支气管镜肺泡灌洗%机械通气
慢性阻塞性肺疾病%支氣管鏡肺泡灌洗%機械通氣
만성조새성폐질병%지기관경폐포관세%궤계통기
COPD%Bronchia Alveolar Lavage%Mechanical Ventilation
目的：探讨支气管镜肺泡灌洗联合序贯机械通气治疗COPD合并呼吸衰竭的临床疗效。方法：选取2011年5月-2013年4月本院收治的58例COPD合并呼吸衰竭患者，按照随机数字表法将其分为对照组和治疗组各29例。对照组给予常规的对症治疗和有创-无创序贯机械通气治疗，治疗组在对照组的基础上行经纤维支气管镜肺泡灌洗。检测两组患者治疗前后的动脉血气分析指标PaO2、PaCO2及pH，同时记录两组患者的机械通气时间、住院时间及并发症的发生率。结果：治疗后，两组患者的PaO2、PaCO2及pH值较治疗前均有明显改善；且治疗组明显优于对照组，差异均有统计学意义（P<0.05）。治疗组患者的机械通气时间（12.5±4.5）d明显少于对照组的（21.5±6.6）d，住院时间（19.7±5.6）d明显少于对照组的（30.8±6.6）d，并发症发生率3.4%明显低于对照组的37.9%，比较差异均有统计学意义（P<0.05）。结论：支气管镜肺泡灌洗联合序贯机械通气治疗COPD合并呼吸衰竭具有疗效确切、安全可靠等优点，可明显缩短机械通气时间，降低并发症的发生率。
目的：探討支氣管鏡肺泡灌洗聯閤序貫機械通氣治療COPD閤併呼吸衰竭的臨床療效。方法：選取2011年5月-2013年4月本院收治的58例COPD閤併呼吸衰竭患者，按照隨機數字錶法將其分為對照組和治療組各29例。對照組給予常規的對癥治療和有創-無創序貫機械通氣治療，治療組在對照組的基礎上行經纖維支氣管鏡肺泡灌洗。檢測兩組患者治療前後的動脈血氣分析指標PaO2、PaCO2及pH，同時記錄兩組患者的機械通氣時間、住院時間及併髮癥的髮生率。結果：治療後，兩組患者的PaO2、PaCO2及pH值較治療前均有明顯改善；且治療組明顯優于對照組，差異均有統計學意義（P<0.05）。治療組患者的機械通氣時間（12.5±4.5）d明顯少于對照組的（21.5±6.6）d，住院時間（19.7±5.6）d明顯少于對照組的（30.8±6.6）d，併髮癥髮生率3.4%明顯低于對照組的37.9%，比較差異均有統計學意義（P<0.05）。結論：支氣管鏡肺泡灌洗聯閤序貫機械通氣治療COPD閤併呼吸衰竭具有療效確切、安全可靠等優點，可明顯縮短機械通氣時間，降低併髮癥的髮生率。
목적：탐토지기관경폐포관세연합서관궤계통기치료COPD합병호흡쇠갈적림상료효。방법：선취2011년5월-2013년4월본원수치적58례COPD합병호흡쇠갈환자，안조수궤수자표법장기분위대조조화치료조각29례。대조조급여상규적대증치료화유창-무창서관궤계통기치료，치료조재대조조적기출상행경섬유지기관경폐포관세。검측량조환자치료전후적동맥혈기분석지표PaO2、PaCO2급pH，동시기록량조환자적궤계통기시간、주원시간급병발증적발생솔。결과：치료후，량조환자적PaO2、PaCO2급pH치교치료전균유명현개선；차치료조명현우우대조조，차이균유통계학의의（P<0.05）。치료조환자적궤계통기시간（12.5±4.5）d명현소우대조조적（21.5±6.6）d，주원시간（19.7±5.6）d명현소우대조조적（30.8±6.6）d，병발증발생솔3.4%명현저우대조조적37.9%，비교차이균유통계학의의（P<0.05）。결론：지기관경폐포관세연합서관궤계통기치료COPD합병호흡쇠갈구유료효학절、안전가고등우점，가명현축단궤계통기시간，강저병발증적발생솔。
Objective:To observe the clinical effects of bronchia alveolar wash combined with mechanical ventilation on COPD patients complicated with respiratory failure.Method:Fifty-eight COPD patients complicated with respiratory failure were selected in our hospital from May 2011 to April 2013,they were randomly divided into the control group and the observation group,29 cases in each group.The control group was given conventional symptomatic treatment and invasive/non-invasive sequential mechanical ventilation,and the observation group was given bronchia alveolar lavage on the basis of the control group.PaO2,PaCO2 and pH of two groups were detected before and after treatment,and mechanical ventilation time,length of stay and incidence of complication were recorded.Result:After treatment,PaO2,PaCO2 and pH of two groups both improved and the observation group were better than the control group,the differences had statistically significant(P<0.05).The duration of mechanical ventilation in the treatment group was (12.5±4.5)d,it was significantly less than that in the control group(21.5±6.6)d,hospitalization time(19.7±5.6)d was significantly less than that in the control group(30.8±6.6)d,the incidence of complications was 3.4%,it was significantly lower than the control group of 37.9%,the differences had statistically significant(P<0.05).Conclusion:Bronchia alveolar lavage combined with mechanical ventilation has curative effect,is safe and reliable,and can significantly shorten mechanical ventilation time and reduce the incidence of complication.
