CAJ | 학술논문

目的了解广东省佛山市三水区正常人群体内血锰(Mn)的本底值水平,评价其对正常人群健康的影响,为中毒原因的调查及疾病的辅助诊断、防控重金属污染提供科学依据.方法采用多阶段分层整群随机抽样的方法,于2009年10月至2010年4月抽取6岁以上非职业接触化学因素的正常人共804人,采集全血样本,采用离子耦合质谱法(ICP-MS)检测.结果正常人群中血Mn参考范围为5.89～18.18 μg/L,均值为(11.36±3.59)μg/L;血Mn浓度水平以16～岁组最高,30～岁组最低;女性血Mn浓度水平高于男性.结论三水地区正常人群体内血Mn的本底值水平较高,年龄和性别之间存在差异.这可能与实验室间差异、人群饮食结构和环境Mn负荷有关,需要进一步调查研究,提示该地区应重视重金属污染的预防控制.
목적 료해광동성불산시삼수구정상인군체내혈맹(Mn)적본저치수평,평개기대정상인군건강적영향,위중독원인적조사급질병적보조진단、방공중금속오염제공과학의거.방법 채용다계단분층정군수궤추양적방법,우2009년10월지2010년4월추취6세이상비직업접촉화학인소적정상인공804인,채집전혈양본,채용리자우합질보법(ICP-MS)검측.결과 정상인군중혈Mn삼고범위위5.89～18.18 μg/L,균치위(11.36±3.59)μg/L;혈Mn농도수평이16～세조최고,30～세조최저;녀성혈Mn농도수평고우남성.결론 삼수지구정상인군체내혈Mn적본저치수평교고,년령화성별지간존재차이.저가능여실험실간차이、인군음식결구화배경Mn부하유관,수요진일보조사연구,제시해지구응중시중금속오염적예방공제.
Objective To understand blood manganese(Mn)background value level in general population at Sanshui district of Foshan,Guangdong province,to assess the effect of manganese on health in these people,and to provide support for screening poisoning causes,disease diagnosis,and prevention and control of heavy metal pollution.Methods Multistage stratified cluster random sampling was used.Blood samples were collected from 804 people older than 6 with non-professional exposure to chemical factors during the period of October 2009 to April 2010.Ion coupling mass spectrometry(ICP-MS)was applied for detection.Results The normal blood Mn reference value ranged from 5.89 to 18.18 μg/L,with a mean value of(11.36±3.59)μg/I;Blood Mn concentration was highest in the group of older than 16 and lowest in the group of older than 30.Blood Mn level was higher in females than in males.Conclusions General population at Sanshui district has a higher level of blood Mn background value;and the value differs in age and sex.The reason why is that may be associated with difference among labs,dietary differences,and environmental Mn loads.It suggests that further research is needed and prevention and control of heavy metal pollution at Sanshui district should be strengthened.