CAJ | 학술논문

目的观察单用乙酰水杨酸和联用低分子肝素钠注射剂（希弗全）治疗不稳定型心绞痛（UAP）的临床疗效．方法将172例UAP患者随机分为治疗组（乙酰水杨酸＋希弗全）和对照组（乙酰水杨酸），疗程1周．结果1周后总有效率治疗组为88．37％，对照组为67．44％（P＜0．05）；观察4周后，治疗组无急性心肌梗死发生，对照组发生6例（9．38％）急性心肌梗死；治疗组未发现明显不良反应．结论用低分子肝素钠注射剂配合常规治疗能有效减低心肌梗死发生率，并显著减少患者心绞痛发作次数，用该方法联合治疗UAP取得了较好的疗效．
목적관찰단용을선수양산화련용저분자간소납주사제（희불전）치료불은정형심교통（UAP）적림상료효．방법장172례UAP환자수궤분위치료조（을선수양산＋희불전）화대조조（을선수양산），료정1주．결과1주후총유효솔치료조위88．37％，대조조위67．44％（P＜0．05）；관찰4주후，치료조무급성심기경사발생，대조조발생6례（9．38％）급성심기경사；치료조미발현명현불량반응．결론용저분자간소납주사제배합상규치료능유효감저심기경사발생솔，병현저감소환자심교통발작차수，용해방법연합치료UAP취득료교호적료효．
Objective To compare the curative effect of acetylsalicylate monotherapy and the combination with Injection Heparinum Natricum Minor Molecularis （IHNMM, Schiffer） on unstable angina pectoris （UAP）. Methods 172 patients with UAP were randomly divided into treatment group （acetylsalicylate ＋ Schiffer） and control group （ acetylsalicylate）, and the course of treatment was one week. Results The total effective rate after one week treatment was 88.37% in the treatment group and 67.44% in the control group （ P 〈 0.05 ） ; after 4 weeks treatment, there was no acute myocardial infarction in the treatment group, but 6 cases with acute myocardial infarction （9.38%） ;no obvious adverse reaction was observed in the treatment group. Conclusion The application of IHNMM combined with the regular therapy can significantly reduce the incidence of acute myocardial infarction, as well as the number of episodes of angina pectoris, the combination therapy is more efficient.