中国兽药杂志
中國獸藥雜誌
중국수약잡지
CHINESE JOURNAL OF VETERINARY DRUG
2012年
3期
56-60
,共5页
病毒%免疫逃逸机制
病毒%免疫逃逸機製
병독%면역도일궤제
virus%evasion mechanisms of the immune response
从各种各样的病毒免疫逃逸机制中归纳概括出病毒逃避宿主抗感染反应的三个大方面,包括病毒逃避体液免疫系统的识别、病毒抑制细胞免疫应答以及病毒干扰免疫效应功能,以期为研制新的病毒疫苗和抗病毒药物提供参考。在宿主和病毒的长期共同进化过程中,宿主发展了各种免疫机制以清除病毒,而病毒则进化出各种免疫逃逸机制来躲避宿主的免疫应答。
從各種各樣的病毒免疫逃逸機製中歸納概括齣病毒逃避宿主抗感染反應的三箇大方麵,包括病毒逃避體液免疫繫統的識彆、病毒抑製細胞免疫應答以及病毒榦擾免疫效應功能,以期為研製新的病毒疫苗和抗病毒藥物提供參攷。在宿主和病毒的長期共同進化過程中,宿主髮展瞭各種免疫機製以清除病毒,而病毒則進化齣各種免疫逃逸機製來躲避宿主的免疫應答。
종각충각양적병독면역도일궤제중귀납개괄출병독도피숙주항감염반응적삼개대방면,포괄병독도피체액면역계통적식별、병독억제세포면역응답이급병독간우면역효응공능,이기위연제신적병독역묘화항병독약물제공삼고。재숙주화병독적장기공동진화과정중,숙주발전료각충면역궤제이청제병독,이병독칙진화출각충면역도일궤제래타피숙주적면역응답。
In this paper, a variety of viral immune escape mechanisms were summarized in three major areas including the recognition of virus evading the humorat immune system, virus suppressing immune responses of cells and function of virus interfering with immune effect so as to provide reference for development of virus vaccine and antiviral drug. In the long - term evolution process of the host and the virus, the host developed various immune systems to eliminate the virus infection while the virus evolved a series of corresponding mechanisms to evade the immune response of the host.