CAJ | 학술논문

[目的]介绍2009甲型H1N1流感病毒的研究进展。[方法]从病毒的分类与宿主,病毒学,分子特征及疫苗等方面简要介绍了2009甲型H1N1流感病毒。[结果]2009年4月初出现的一种新型甲型（H1N1）流感病毒通过人-人传播迅速蔓延全球,该病毒包含一组新的基因片段,已知的最接近的前体为在猪体内发现的病毒。该病毒似乎保留着重新感染猪的潜力从而可能继续与猪源病毒发生重组。所有已注册的2009甲型流感疫苗均在对志愿者的临床试验中测试了安全性和免疫原性,发现所有疫苗都是安全的,并且单剂量的疫苗给药后引起保护性抗体反应。[结论]为进一步研究2009甲型H1N1流感病毒提供依据。
[목적]개소2009갑형H1N1류감병독적연구진전。[방법]종병독적분류여숙주,병독학,분자특정급역묘등방면간요개소료2009갑형H1N1류감병독。[결과]2009년4월초출현적일충신형갑형（H1N1）류감병독통과인-인전파신속만연전구,해병독포함일조신적기인편단,이지적최접근적전체위재저체내발현적병독。해병독사호보류착중신감염저적잠력종이가능계속여저원병독발생중조。소유이주책적2009갑형류감역묘균재대지원자적림상시험중측시료안전성화면역원성,발현소유역묘도시안전적,병차단제량적역묘급약후인기보호성항체반응。[결론]위진일보연구2009갑형H1N1류감병독제공의거。
[Objective] The paper was to introduce the research progress of 2009 influenza A virus. [Method] 2009 influenza A virus was introduced from the aspects of classification and host, virology, molecular characteristics and vaccine. [Result] A novel influenza A/H1N1 virus emerged in early April 2009 quickly spread worldwide through human-to-human transmission. The virus contained a group of novel gene segments, the nearest known precursor was the virus found in swine. The virus appeared to retain the potential to infect swine again and thus continued reassort with swine viruses. All registered 2009 influenza A vaccines were tested for safety and immunogenicity in clinical trials on human volunteers, and all vaccines were found to be safe, single dose of vaccine could cause protective antibody responses. [Conclusion] The paper provided basis for further study on 2009 influenza A virus.