激光杂志
激光雜誌
격광잡지
LASER JOURNAL
2012年
2期
71-72
,共2页
李敏%陈方淳%黄孝庆%王竹行
李敏%陳方淳%黃孝慶%王竹行
리민%진방순%황효경%왕죽행
复发性阿弗他溃疡%中医证型%免疫
複髮性阿弗他潰瘍%中醫證型%免疫
복발성아불타궤양%중의증형%면역
recurrent aphthous ulcer(RAU)%Chinese medicine syndrome types%immunity
目的：观察不同中医证型复发性阿弗他溃疡（Recurrent Aphthous Ulcer,RAU）患者的免疫状况,探讨其中医证型与免疫的关系,为临床医师初步判断RAU患者免疫状况及合理用药提供参考。方法：97例RAU患者按中医辨证的方法分成胃火上炎型、阴虚火旺型、心脾积热型和脾肾阳虚型,分别检测其体液免疫及细胞免疫,对结果进行统计分析。结果：①胃火上炎型的RAU患者人数最多（44.3%）。②RAU患者外周血细胞免疫指标总体表现为体液免疫正常和细胞免疫的降低,其中CD3、CD4、和CD4/CD8水平分别降低86.60%、79.38%、和76.29%）,③不同中医证型RAU患者组间比较显示：心脾积热型的CD3水平较其他三型低,组间差异具有统计学意义（P〈0.05）;脾肾阳虚型的CD3水平较其他三型高,组间差异具有统计学意义（P〈0.05）;阴虚火旺型的CD4、和CD4/CD8水平较胃火上炎型和脾肾阳虚型低,组间差异具有统计学意义（P〈0.05）;不同证型RAU患者的CD8水平差异无统计学意义（P〉0.05）。结论：RAU患者的免疫状态以细胞免疫紊乱为主：RAU患者的中医证型和免疫存在一定的相关性。
目的：觀察不同中醫證型複髮性阿弗他潰瘍（Recurrent Aphthous Ulcer,RAU）患者的免疫狀況,探討其中醫證型與免疫的關繫,為臨床醫師初步判斷RAU患者免疫狀況及閤理用藥提供參攷。方法：97例RAU患者按中醫辨證的方法分成胃火上炎型、陰虛火旺型、心脾積熱型和脾腎暘虛型,分彆檢測其體液免疫及細胞免疫,對結果進行統計分析。結果：①胃火上炎型的RAU患者人數最多（44.3%）。②RAU患者外週血細胞免疫指標總體錶現為體液免疫正常和細胞免疫的降低,其中CD3、CD4、和CD4/CD8水平分彆降低86.60%、79.38%、和76.29%）,③不同中醫證型RAU患者組間比較顯示：心脾積熱型的CD3水平較其他三型低,組間差異具有統計學意義（P〈0.05）;脾腎暘虛型的CD3水平較其他三型高,組間差異具有統計學意義（P〈0.05）;陰虛火旺型的CD4、和CD4/CD8水平較胃火上炎型和脾腎暘虛型低,組間差異具有統計學意義（P〈0.05）;不同證型RAU患者的CD8水平差異無統計學意義（P〉0.05）。結論：RAU患者的免疫狀態以細胞免疫紊亂為主：RAU患者的中醫證型和免疫存在一定的相關性。
목적：관찰불동중의증형복발성아불타궤양（Recurrent Aphthous Ulcer,RAU）환자적면역상황,탐토기중의증형여면역적관계,위림상의사초보판단RAU환자면역상황급합리용약제공삼고。방법：97례RAU환자안중의변증적방법분성위화상염형、음허화왕형、심비적열형화비신양허형,분별검측기체액면역급세포면역,대결과진행통계분석。결과：①위화상염형적RAU환자인수최다（44.3%）。②RAU환자외주혈세포면역지표총체표현위체액면역정상화세포면역적강저,기중CD3、CD4、화CD4/CD8수평분별강저86.60%、79.38%、화76.29%）,③불동중의증형RAU환자조간비교현시：심비적열형적CD3수평교기타삼형저,조간차이구유통계학의의（P〈0.05）;비신양허형적CD3수평교기타삼형고,조간차이구유통계학의의（P〈0.05）;음허화왕형적CD4、화CD4/CD8수평교위화상염형화비신양허형저,조간차이구유통계학의의（P〈0.05）;불동증형RAU환자적CD8수평차이무통계학의의（P〉0.05）。결론：RAU환자적면역상태이세포면역문란위주：RAU환자적중의증형화면역존재일정적상관성。
Objective：To observe the correlation between RAU＇s Chinese medicine Syndrome Types and immunity,offering reference to clinician for prelimilary judgement of RAU＇s immunity and clinical treatment.Methods： 97 RAU patients were grouped under four syndromes： fire excess of stomach,yin-deficiency and fire-excess,accumulation of heart and spleen,spleen-kidney yang deficiency according to the method of Chinese medical differentiations.Penpheral blood parameters about immune function were examined in order to obtain the objective examination results of the immune status.The data was statistically analyzed.Result：Most of the patients went to fire excess of stomach syndrome（44.3%）.On the whole,CD3,CD4,and CD4/CD8 levels were decreased among the four syndromes（thc rate of decrease is respectively 86.60%4 79.38%,76.29%）,in the accumulation of heart and splenic syndrome,CD3 decreased significantly than the rest syndromes（p0.05）;In the spleen-kidney yang deficiency syndrome,CD3 increased significantly than the other three types（p0.05）;In the yin-deficiency and fire-excess,CD4 and CD4/CD8 decreased significantly than the fire excess of stomach and the spleen-kidney yang deficiency syndrome（p0.05）.No statistical difference had been reached so far among the different type of CD8（p0.05）.Conclusions： RAU patient＇s immune status is mainly of cell-based immune disorders;there is correlation between RAU＇s Chinese Medicine Differentiations and immunity to some degree.
