CAJ | 학술논문

目的比较不同血糖水平急性脑梗死患者血栓调节蛋白水平.方法选择急性脑梗死患者489例,其中无糖尿病237例(无糖尿病组),糖尿病血糖控制良好117例(血糖良好组),糖尿病血糖控制不佳135例(血糖不佳组),比较各组间血栓调节蛋白水平.结果无糖尿病组血栓调节蛋白水平为(2.66±1.20) μg/L,血糖良好组为(2.80±1.43) μg/L,血糖不佳组为(3.22±1.60)μg/L,三组间血栓调节蛋白水平呈逐渐升高趋势,差异有统计学意义(P=0.030).组间两两比较,无糖尿病组血栓调节蛋白水平与血糖不佳组比较差异有统计学意义(P=0.008).结论急性脑梗死患者血糖控制不佳时血栓调节蛋白水平升高.
목적 비교불동혈당수평급성뇌경사환자혈전조절단백수평.방법 선택급성뇌경사환자489례,기중무당뇨병237례(무당뇨병조),당뇨병혈당공제량호117례(혈당량호조),당뇨병혈당공제불가135례(혈당불가조),비교각조간혈전조절단백수평.결과 무당뇨병조혈전조절단백수평위(2.66±1.20) μg/L,혈당량호조위(2.80±1.43) μg/L,혈당불가조위(3.22±1.60)μg/L,삼조간혈전조절단백수평정축점승고추세,차이유통계학의의(P=0.030).조간량량비교,무당뇨병조혈전조절단백수평여혈당불가조비교차이유통계학의의(P=0.008).결론 급성뇌경사환자혈당공제불가시혈전조절단백수평승고.
Objective To compare the levels of thrombomodulin in acute cerebral infarction patients with different blood glucose levels.Methods Four hundred and eighty-nine patients with acute cerebral infarction were selected including 237 patients of non-diabetes (non-diabetes group),117 patients of diabetes and HbA1c ≤7.0％(diabetes controlled well group) and 135 patients of diabetes and HbA1c ＞7.0％ (diabetes controlled badly group).The level of thrombomodulin was assayed by enzyme-linked immunosorbent assay and compared among three groups.Results The level of thrombomodulin was (2.66 ± 1.20) μg/L in non-diabetes group,(2.80 ± 1.43) μg/L in diabetes controlled well group,(3.22 ±1.60) μ g/L in diabetes controlled badly group.There was the increasing of thrombomodulin among non-diabetes group,diabetes controlled well group and diabetes controlled badly group (P =0.030).There was difference between non-diabetes group and diabetes controlled badly group (P =0.008).Conclusion There is the increasing of thrombomodulin in patients with acute cerebral infarction when their blood glucose rising.