中兽医医药杂志
中獸醫醫藥雜誌
중수의의약잡지
Journal of Traditional Chinese Veterinary Medicine
2012年
2期
8-12
,共5页
徐登基%兰新财%缪雪荣%肖琛闻%何绣锦%施佩
徐登基%蘭新財%繆雪榮%肖琛聞%何繡錦%施珮
서등기%란신재%무설영%초침문%하수금%시패
速派%芍药苷%丹皮酚%高效液相色谱法%正交试验
速派%芍藥苷%丹皮酚%高效液相色譜法%正交試驗
속파%작약감%단피분%고효액상색보법%정교시험
Super granules%paeoniflorin%paeonol%HPLC%orthogonal design
目的：优化速派颗粒中牡丹皮活性成分的提取工艺。方法：以芍药苷和丹皮酚为指标,通过正交试验考察不同因素和水平对提取工艺的影响。结果：芍药苷的最佳提取工艺是70%乙醇、提取温度80℃、乙醇用量12倍、提取时间0.5 h;丹皮酚的最佳提取工艺是蒸馏时间为4 h、收集8倍液量、0℃冷藏36 h。结论：该提取工艺合理、可行,可为大生产提供实验依据。
目的：優化速派顆粒中牡丹皮活性成分的提取工藝。方法：以芍藥苷和丹皮酚為指標,通過正交試驗攷察不同因素和水平對提取工藝的影響。結果：芍藥苷的最佳提取工藝是70%乙醇、提取溫度80℃、乙醇用量12倍、提取時間0.5 h;丹皮酚的最佳提取工藝是蒸餾時間為4 h、收集8倍液量、0℃冷藏36 h。結論：該提取工藝閤理、可行,可為大生產提供實驗依據。
목적：우화속파과립중모단피활성성분적제취공예。방법：이작약감화단피분위지표,통과정교시험고찰불동인소화수평대제취공예적영향。결과：작약감적최가제취공예시70%을순、제취온도80℃、을순용량12배、제취시간0.5 h;단피분적최가제취공예시증류시간위4 h、수집8배액량、0℃랭장36 h。결론：해제취공예합리、가행,가위대생산제공실험의거。
Objective： To optimize the extracting process of tree peony bark from Super granules.Methods： Orthogonal experiment was carried out with paeoniflorin and paeonol as the detective marker.Results： The optimum extracting condition for paeoniflorin was that adding twelve fold volume of 70% ethanol at 80 ℃ for 0.5 hour;while optimum extracting condition for paeonol was that four hours of distillation,eight fold volume of collection liquid and 36 hours of refrigeration at 0 ℃.Conclusion： The suitable and practicable extracting process could provide experiment data for factory production.
