世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2014年
1期
35-36
,共2页
慢性阻塞性肺疾病%呼吸衰竭%纳洛酮%无创正压通气
慢性阻塞性肺疾病%呼吸衰竭%納洛酮%無創正壓通氣
만성조새성폐질병%호흡쇠갈%납락동%무창정압통기
chronic obstructive pulmonary%disease respiratory failure%naloxone%noninvasive positive pressure ventilation
目的：探讨慢性阻塞性肺疾病合并呼吸衰竭的临床特点及治疗疗效。方法分析了我院对收治的32例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者采用纳洛酮联合无创正压通气治疗的临床资料，并与同期给于常规综合治疗的32例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的住院患者作对照。结果观察组治疗总有效率为93.75%，对照组为71.88%，两组差异有统计学意义(P <0.05)。观察组患者治疗后 pH 值、Pao2、Paco2较治疗前明显改善，比较差异有统计学意义(P<0.05)，观察组与对照组比较，差异有统计学意义(P <0.05)。两组患者治疗前后心率及呼吸频率均好转，但观察组心率及呼吸频率治疗前后比较差异有统计学意义（P <0.05）。结论纳洛酮联合无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者临床疗效较好，能明显改善临床症状，降低死亡率。
目的：探討慢性阻塞性肺疾病閤併呼吸衰竭的臨床特點及治療療效。方法分析瞭我院對收治的32例慢性阻塞性肺疾病閤併Ⅱ型呼吸衰竭患者採用納洛酮聯閤無創正壓通氣治療的臨床資料，併與同期給于常規綜閤治療的32例慢性阻塞性肺疾病閤併Ⅱ型呼吸衰竭的住院患者作對照。結果觀察組治療總有效率為93.75%，對照組為71.88%，兩組差異有統計學意義(P <0.05)。觀察組患者治療後 pH 值、Pao2、Paco2較治療前明顯改善，比較差異有統計學意義(P<0.05)，觀察組與對照組比較，差異有統計學意義(P <0.05)。兩組患者治療前後心率及呼吸頻率均好轉，但觀察組心率及呼吸頻率治療前後比較差異有統計學意義（P <0.05）。結論納洛酮聯閤無創正壓通氣治療慢性阻塞性肺疾病閤併Ⅱ型呼吸衰竭患者臨床療效較好，能明顯改善臨床癥狀，降低死亡率。
목적：탐토만성조새성폐질병합병호흡쇠갈적림상특점급치료료효。방법분석료아원대수치적32례만성조새성폐질병합병Ⅱ형호흡쇠갈환자채용납락동연합무창정압통기치료적림상자료，병여동기급우상규종합치료적32례만성조새성폐질병합병Ⅱ형호흡쇠갈적주원환자작대조。결과관찰조치료총유효솔위93.75%，대조조위71.88%，량조차이유통계학의의(P <0.05)。관찰조환자치료후 pH 치、Pao2、Paco2교치료전명현개선，비교차이유통계학의의(P<0.05)，관찰조여대조조비교，차이유통계학의의(P <0.05)。량조환자치료전후심솔급호흡빈솔균호전，단관찰조심솔급호흡빈솔치료전후비교차이유통계학의의（P <0.05）。결론납락동연합무창정압통기치료만성조새성폐질병합병Ⅱ형호흡쇠갈환자림상료효교호，능명현개선림상증상，강저사망솔。
Objective clinical characteristics and treatment of chronic obstructive pulmonary disease with respiratory failure. Methods Patients in our hospital in 32 cases of chronic obstructive pulmonary disease with type ii respiratory failure with naloxone combined with non invasive positive pressure ventilation in the treatment of clinical data, 32 cases of chronic obstructive pulmonary disease with type ii respiratory failure and compared to conventional therapy in the hospital were as the control. Results Observation group treatment the total effective rate was 93.75%, control group was 71.88%, the difference between the two groups was statistically significant (P < 0.05). observation group after treatment in patients with pH, Pao2, Paco2 obviously improved than before treatment, compare the difference was statistically significant (P < 0.05), the observation group compared with control group, the difference was statistically significant (P < 0.05). in the two groups before and after treatment in patients with heart rate and breathing rate are improved, but the observation group of heart rate and breathing rate before and after treatment comparison difference was statistically significant (P < 0.05). Conclusion naloxone combined noninvasive positive pressure ventilation in patients with chronic obstructive pulmonary disease combined type Ⅱ respiratory failure patient clinical curative effect is good, can significantly improve the clinical symptoms, reduce mortality.
