CAJ | 학술논문

目的：探讨患者血清降钙素原（Pct）水平对区别血培养生长革兰阳性菌及阴性菌的临床意义。方法对 icU 患者血培养阳性者分为革兰阴性菌组及革兰阳性菌组，每组患者各25例，对两组患者血清降钙素原进行定量测定，并对定量测定结果进行统计学比较。结果血培养生长革兰阴性菌患者 Pct 定量为（60.556±38.816）ng/ml，显著高于革兰阳性菌组 Pct（15.397±15.657）ng/ml，差异有统计学意义（P ＜0.05）。结论革兰阴性菌血流感染患者的降钙素原水平明显高于革兰阳性菌血流感染患者，Pct 测定有利于早期判断细菌感染的类别，指导早期抗菌药物选择。
목적：탐토환자혈청강개소원（Pct）수평대구별혈배양생장혁란양성균급음성균적림상의의。방법대 icU 환자혈배양양성자분위혁란음성균조급혁란양성균조，매조환자각25례，대량조환자혈청강개소원진행정량측정，병대정량측정결과진행통계학비교。결과혈배양생장혁란음성균환자 Pct 정량위（60.556±38.816）ng/ml，현저고우혁란양성균조 Pct（15.397±15.657）ng/ml，차이유통계학의의（P ＜0.05）。결론혁란음성균혈류감염환자적강개소원수평명현고우혁란양성균혈류감염환자，Pct 측정유리우조기판단세균감염적유별，지도조기항균약물선택。
Objective To investigate the clinical significance of serum procalcitonin (PCT) levels in distinguishing growth of Gram-positive and gram negative bacteria in blood culture.Methods icU patients with positive blood culture were divided into Gram-negative bacteria group and Gram-positive bacteria group, with 25 cases in each group. the serum procalcitonin in two groups were detected by quantitative determination, results of which were compared in statistics. Results the Pct level in blood culture results of growth of Gram-negative bacteria patients was (60.556 ± 38.816) ng / ml, which was significantly higher than (15.397 ± 15.657) ng / ml in Gram-positive bacteria group. The difference was statistically significant (P <0.05 ). Conclusion The procalcitonin level in patients with bloodstream Gram-negative bacteria infections was significantly higher than that in patients with bloodstream Gram-positive bacteria infections. determination of Pct was in favor of judging early bacterial infection category and guiding the early antibacterial agent selection.