北华大学学报：自然科学版
北華大學學報：自然科學版
북화대학학보：자연과학판
Journal of Beihua University(Natural Science)
2012年
1期
65-67
,共3页
白桦树皮%白桦酯醇%白桦酯酸%降血脂%脂必妥
白樺樹皮%白樺酯醇%白樺酯痠%降血脂%脂必妥
백화수피%백화지순%백화지산%강혈지%지필타
white birch bark%betulin%betulinic acid%hypolipidemic%Zhinbiticose
目的研究白桦树皮提取物（BH）的降血脂作用．方法分正常组、模型组、BH给药组：高（300mg／kg）、中（200mg／kg）、低（100mg／kg）剂量和阳性对照组：脂必妥（300mg／kg）．预防给药7d，末次给药2h后，腹腔注射75％蛋黄乳液制作小鼠高脂血症模型，造模12h后测定不同剂量的BH对小鼠血脂水平的影响．结果白桦树皮提取物能够显著降低小鼠血清中TC，TG，LDL-C浓度，显著升高HDL-C．结论白桦树皮提取物具有明显的降血脂作用．
目的研究白樺樹皮提取物（BH）的降血脂作用．方法分正常組、模型組、BH給藥組：高（300mg／kg）、中（200mg／kg）、低（100mg／kg）劑量和暘性對照組：脂必妥（300mg／kg）．預防給藥7d，末次給藥2h後，腹腔註射75％蛋黃乳液製作小鼠高脂血癥模型，造模12h後測定不同劑量的BH對小鼠血脂水平的影響．結果白樺樹皮提取物能夠顯著降低小鼠血清中TC，TG，LDL-C濃度，顯著升高HDL-C．結論白樺樹皮提取物具有明顯的降血脂作用．
목적연구백화수피제취물（BH）적강혈지작용．방법분정상조、모형조、BH급약조：고（300mg／kg）、중（200mg／kg）、저（100mg／kg）제량화양성대조조：지필타（300mg／kg）．예방급약7d，말차급약2h후，복강주사75％단황유액제작소서고지혈증모형，조모12h후측정불동제량적BH대소서혈지수평적영향．결과백화수피제취물능구현저강저소서혈청중TC，TG，LDL-C농도，현저승고HDL-C．결론백화수피제취물구유명현적강혈지작용．
Objective To study hypolipidemic effects of white birch bark extract. Method The white birch bark extract （BH） at the dose of 300 mg/kg was given to mice in high-dose group,200 mg/kg in middle-dose group and 100 mg/kg in low-dose group, and Zhinbitieose at the dose of 300 mg/kg in the positive control group orally for 7 days for the prophylaxis of lipidemic disorders. At 2h after the final administration,75% egg yolk emulsion was intraperitoneally given to the mice in all groups except for the normal group to establish the mouse model of hyperlipidemia. Effects of BH at the different doses on lipid levels in blood in mice were measured at 12h after the modeling. Results The white birch bark extract could significantly reduce serum TC, TG and LDL-C contents, and significantly elevate HDL-C level. Conclusion The white birch bark extract can produce significantly hypolipidemic effect on mice.
