CAJ | 학술논문

目的：探讨降钙素原在普外科创伤患者术后全身炎症反应综合征中的应用。方法选择广东省东莞市东莞寮步医院普外科收治的100例创伤术后发生全身炎症反应综合征的患者，随机均分为2组。降钙素原组使用抗生素依据血清降钙素原浓度，对照组使用抗生素依据抗生素使用指南。记录两组治疗有效例数和死亡例数，记录2组使用抗生素例数，记录2组住院时间和住院费用。结果2组患者的有效率和死亡率比较，差异无统计学意义；降钙素原组使用抗生素的患者比对照组少，差异有统计学意义（P＜0.05）；2组患者住院时间比较，差异无统计学意义；降钙素原组患者的住院费用少于对照组，差异有统计学意义（P＜0.05）。结论应用降钙素原指导抗生素使用，可使患者抗生素使用率降低和医疗费用减少。
목적：탐토강개소원재보외과창상환자술후전신염증반응종합정중적응용。방법선택광동성동완시동완료보의원보외과수치적100례창상술후발생전신염증반응종합정적환자，수궤균분위2조。강개소원조사용항생소의거혈청강개소원농도，대조조사용항생소의거항생소사용지남。기록량조치료유효례수화사망례수，기록2조사용항생소례수，기록2조주원시간화주원비용。결과2조환자적유효솔화사망솔비교，차이무통계학의의；강개소원조사용항생소적환자비대조조소，차이유통계학의의（P＜0.05）；2조환자주원시간비교，차이무통계학의의；강개소원조환자적주원비용소우대조조，차이유통계학의의（P＜0.05）。결론응용강개소원지도항생소사용，가사환자항생소사용솔강저화의료비용감소。
Objective To investigate the application of procalcitonin in the trauma patients underwent systemic inflammatory response syndrome after operation in general surgery department.Method One hundred trauma patients underwent systemic inflammatory response syndrome after operation in general surgery department were divided into two groups: procalcitonin group and control group. Antibiotics were used according to serum procalcitonin concentration in the procalcitonin group. Antibiotics were used according to antibiotic use guide in the control group. The effective rate, mortality, antibiotic use rate, hospital stays, hospitalization expenses in both groups were recorded.Results There were no significant difference in the effective rate and mortality between two groups.The antibiotic use rate in the procalcitonin group was lower than it in the control group(P<0.05). There were no significant difference in the hospital stays between two groups.The hospitalization expenses in the procalcitonin group were less than those in the control group(P<0.05).Conclusion Application of procalcitonin in antibiotics use can decrease the antibiotic use rate and the hospitalization expenses.