CAJ | 학술논문

目的：探讨银杏达莫注射液治疗脑动脉硬化脑供血不全的临床疗效。方法选取本院神经内科收治的116例脑动脉硬化脑供血不全病例，随机分为观察组与对照组各58例，其中观察组选用银杏达莫注射液（5%葡萄糖500ml+20ml/次，2次/d）治疗；对照组选用复方丹参注射液（5%葡萄糖250ml+20ml/d）治疗，分析比较两组病例的红细胞压积、全血比黏度、凝血功能（Pt,aPtt）等血流变学指标差异性。结果在红细胞压积、全血比黏度、Pt 及 aPtt 等血流变学指标控制效果中观察组优于对照组，且有差异性统计学意义（P ＜0.05）。结论银杏达莫注射液能有效改变血流变学及改善慢性脑供血不足患者的临床症状，安全可靠。
목적：탐토은행체막주사액치료뇌동맥경화뇌공혈불전적림상료효。방법선취본원신경내과수치적116례뇌동맥경화뇌공혈불전병례，수궤분위관찰조여대조조각58례，기중관찰조선용은행체막주사액（5%포도당500ml+20ml/차，2차/d）치료；대조조선용복방단삼주사액（5%포도당250ml+20ml/d）치료，분석비교량조병례적홍세포압적、전혈비점도、응혈공능（Pt,aPtt）등혈류변학지표차이성。결과재홍세포압적、전혈비점도、Pt 급 aPtt 등혈류변학지표공제효과중관찰조우우대조조，차유차이성통계학의의（P ＜0.05）。결론은행체막주사액능유효개변혈류변학급개선만성뇌공혈불족환자적림상증상，안전가고。
Objective to explore the clinical effect of Ginkgo dipyridamole injection in treatment of cerebral arteriosclerosis combined with cerebral blood supply insufficiency. Methods 116 patients with cerebral arteriosclerosis combined with cerebral blood supply insufficiency admitted in department of nerve internal medicine in our hospital were randomly divided into observation group and control group with 58 cases in each group. the patients in the observation group were treated with Ginkgo dipyridamole injection (500ml+20ml/ of 5% glucose, twice a day), and patients in the control group were given compound danshen injection (250ml+20ml of 5% glucose once a day). then the differences of hemorrheology indicators including hematocrit, whole blood viscosity and coagulation function (Pt, aPtt) were analyzed and compared. Results the control effects on hematocrit, whole blood viscosity, Pt and aPtt in the observation group was better than that of control group and there were statistically significant differences (P < 0.05).Conclusion Ginkgo dipyridamole injection has the effect of changing hemorrheology indicators and improving the clinical symptoms of patients with chronic cerebral blood supply insufficiency, with safe and reliable advantages.