世界最新医学信息文摘（连续型电子期刊）
世界最新醫學信息文摘（連續型電子期刊）
세계최신의학신식문적（련속형전자기간）
World Latest Medicine Information
2014年
29期
38-39
,共2页
急性缺血性脑卒中%扩容治疗%预后影响
急性缺血性腦卒中%擴容治療%預後影響
급성결혈성뇌졸중%확용치료%예후영향
acute ischemic stroke%Hypervolemic therapy%prognosis outcomes
目的：研究扩容治疗对急性缺血性脑卒中患者预后的影响。方法回顾性分析研究2011年1月至2013年12月本院神经内科收治的160例急性缺血性脑卒中患者病例资料，随机分为对照组与观察组各80例，两组病例在急性缺血性脑卒常规治疗基础上，对照组给予尿激酶溶栓治疗；观察组在对照治疗基础上增加中分子羟乙基淀粉注射液500ml 静脉滴注扩容治疗。对比分析两组患者治疗前后的血液流变学（血浆粘度、高切粘度、低切粘度）及血脂（总胆固醇及甘油三酯）等指标变化。结果两组病例治疗效果在血液流变学（血浆粘度、高切粘度、低切粘度）及血脂（总胆固醇及甘油三酯）等指标变化中观察组均优于对照组，两组患者经不同方法治疗后临床治疗总有效率观察组（97.50）优于对照组（85.00%），对比分析结果具有统计学意义（P ＜0.05）。结论对于急性缺血性脑卒中患者采用中分子羟乙基淀粉扩容治疗预后良好，临床效果显著，对改善短期及长期神经功能预后恢复具有重要的影响作用。
目的：研究擴容治療對急性缺血性腦卒中患者預後的影響。方法迴顧性分析研究2011年1月至2013年12月本院神經內科收治的160例急性缺血性腦卒中患者病例資料，隨機分為對照組與觀察組各80例，兩組病例在急性缺血性腦卒常規治療基礎上，對照組給予尿激酶溶栓治療；觀察組在對照治療基礎上增加中分子羥乙基澱粉註射液500ml 靜脈滴註擴容治療。對比分析兩組患者治療前後的血液流變學（血漿粘度、高切粘度、低切粘度）及血脂（總膽固醇及甘油三酯）等指標變化。結果兩組病例治療效果在血液流變學（血漿粘度、高切粘度、低切粘度）及血脂（總膽固醇及甘油三酯）等指標變化中觀察組均優于對照組，兩組患者經不同方法治療後臨床治療總有效率觀察組（97.50）優于對照組（85.00%），對比分析結果具有統計學意義（P ＜0.05）。結論對于急性缺血性腦卒中患者採用中分子羥乙基澱粉擴容治療預後良好，臨床效果顯著，對改善短期及長期神經功能預後恢複具有重要的影響作用。
목적：연구확용치료대급성결혈성뇌졸중환자예후적영향。방법회고성분석연구2011년1월지2013년12월본원신경내과수치적160례급성결혈성뇌졸중환자병례자료，수궤분위대조조여관찰조각80례，량조병례재급성결혈성뇌졸상규치료기출상，대조조급여뇨격매용전치료；관찰조재대조치료기출상증가중분자간을기정분주사액500ml 정맥적주확용치료。대비분석량조환자치료전후적혈액류변학（혈장점도、고절점도、저절점도）급혈지（총담고순급감유삼지）등지표변화。결과량조병례치료효과재혈액류변학（혈장점도、고절점도、저절점도）급혈지（총담고순급감유삼지）등지표변화중관찰조균우우대조조，량조환자경불동방법치료후림상치료총유효솔관찰조（97.50）우우대조조（85.00%），대비분석결과구유통계학의의（P ＜0.05）。결론대우급성결혈성뇌졸중환자채용중분자간을기정분확용치료예후량호，림상효과현저，대개선단기급장기신경공능예후회복구유중요적영향작용。
Objective to study the hypervolemic therapy on the prognosis of patients with acute ischemic stroke. Methods the data of 160 cases of patients with acute ischemic stroke admitted in department of nerve internal medicine in our hospital from January 2011 to december 2013 were retrospectively studied. they were randomly divided into control group and observation group with 80 cases in each group, and were treated on the basis of routine therapy on acute ischemic stroke. Patients in the control group were given uric kinase thrombolytic therapy, while patients in observation group received molecule hydroxyethyl starch injection with 500ml intravenous drip for hypervolemic therapy. the hemorheology (plasma viscosity, high shear viscosity and low shear viscosity) and blood lipids levels (total cholesterol and triglycerides) changes were analyzed and compared before and after treatment.Results the treatment effect of hemorheology (blood plasma viscosity, high shear viscosity, low shear viscosity) and blood lipid levels (total cholesterol and triglyceride) in the observation group were better than that in control group. after the treatment by two kinds of methods, total clinical effective rate of observation group (97.50) was better than that of control group (85.00%), with statistical significance (P < 0.05).Conclusion the molecular hydroxyethyl starch in hypervolemic therapy in treatment of patients with acute ischemic stroke can get good prognosis, and its clinical effect is remarkable. it plays an important role in improving the prognosis of short-term or long-term neurologic recovery.
